Children with Survival Analysis of Severe Motor and Intellectual Disabilities Syndrome

严重运动和智力障碍综合征儿童的生存分析

• 批准号: 11670390
• 负责人: YOKOYAMA Eise
• 金额: $ 1.86万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11670390/
• 关键词: SMIDS; Survival Analysis; Prognosis

Children with Severe Motor and Intellectual Disabilities Syndrome(SMIDS) cared for in national hospitals were studied concerning their survival rate and prognosis. The 1988 nationalwide survey data on personal check lists for patients in national hospital. They had remained under observation for 8 years until 1955, when 6,005 were found to have survived and 515 died. Results were as follows ;1. Mortality rate was highest 14.9% for patients in Oshima's Category I.2. Survival analysis )by Kaplan-Meire methods) : Survival rate by age stood at 80.1 for children aged 0 to 9. The rate by sex amounted to 90.5% for males and 92.1% for females. The rate by posture was found to be 76.0% for those with unstable necks irrespective of posture. The rate by movement method was 79.7% for those who were unable to move to another place. The rate by convulsion frequency was estimated at 82.8% for those who had at least 10 seizers in the last 2 months. The rate by manual function stood at 73.8% for those whose hands remained clasped or immobile. The rate by mobility impaired was 86.0% for the bed-ridden. The rate by intelligence was relatively high, the lowest being 91% for those with an IQ of 20 or below. The rate by feeding method was estimated at 65.5% for those with tube feeding.3.The influence of those factors on prognosis was evaluated by means of Cox's proportional hazard model. Covariates found to be significantly correlative included : sex ; movement method ; feeding type ; morbidity impairment ; manual function ; age.

研究了在国家医院接受的严重运动和智力障碍综合症（SMID）的儿童有关其生存率和预后的研究。 1988年国家医院患者的个人检查清单的国家调查数据。直到1955年，他们一直在观察8年，当时发现6,005人幸存下来，有515人死亡。结果如下; 1。 Oshima类I.2患者的死亡率最高14.9％。生存分析）通过Kaplan-Meire方法）：年龄为0至9岁的儿童的生存率为80.1。男性的性别率为90.5％，女性为92.1％。发现颈部不稳定的人的姿势速率为76.0％，而与姿势无关。对于那些无法搬到另一个地方的人来说，按运动方法的比率为79.7％。在过去2个月中至少有10个夺取者的人估计抽搐频率的速率为82.8％。手动功能的速率为73.8％，因为那些手动握紧或不动的人的速度为73.8％。卧床不起的流动性损害率为86.0％。智能的速度相对较高，智商为20或以上的人最低91％。估计喂食者的喂养方法的速率为65.5％。3。这些因素对预后的影响通过COX的比例危害模型评估。事实发现的协变量包括：性别：性别；运动方法；进食类型；发病障碍；手动功能；年龄。