Physiological and morphological studies on microcirculation of the eye during accommodation

调节过程中眼微循环的生理和形态学研究

• 批准号: 60440080
• 负责人: TOKORO Takashi
• 金额: $ 10.5万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (A)
• 财政年份: 1985
• 资助国家: 日本
• 起止时间: 1985 至 1987
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60440080/
• 关键词: Scanning electron microscopy; Microcirculation of the eye; Aqueous outflow; Infusion method of plastic material; ciliary body; accommodation; 赤外線ファコメータ; 虹彩; 樹脂; 注入法

1. We examined the three-dimentional structure of the ciliary vessels and of the outflow routes for aqueous humor in cynomolgus monkeys with the corrosion cast technique and scanning electron microscopy.(1) Arterial supply of the ciliary body had two pathways which were the long posterior and the anterior ciliary arteries, but no venous drainage system was seen without the vortex system. The collector channeles of Schlemm's canal had no communication with the ciliary circulation.(2) The casting material infused into the anterior chamber, the method of which was developed by ourselves, was filled in the main and the uveoscleral routes.In the uveoscleral outflow, the cast reached to suprachoroidal space passing through the trabecular meshwork, the ciliary muscle space, small pores in the ciliary muscle bundles and the supraciliary space.(3) The pores in the ciliary muscle bundles became narrowing after instillation of atropine (accommodation relaxation) or ilocarpine (accommodation spasm).2. Relationship between the microfluctuation of accommodation in the human eyeby an infrared optometer and the pulsatiion of heart was found. Using the samemethod, accommodation of the myopia was measured. As the results, the accommodative responses of the corrected myopia by spectacles were smaller than those ofemmetropia.

1.采用腐蚀铸型技术和扫描电镜对食蟹猴睫状体血管的三维结构和房水流出通道进行了观察。(1)睫状体的动脉供应有两条途径，即长的和长的。睫状后动脉和前睫状动脉，但在没有涡流系统的情况下没有看到静脉引流系统。施莱姆管的收集通道与睫状体循环不相通。(2)采用自行开发的方法将浇铸材料注入前房，填充在主干路和葡萄膜巩膜通道中。在葡萄膜巩膜流出处，石膏穿过小梁网、睫状肌间隙、睫状肌束中的小孔和睫状上间隙到达脉络膜上间隙。(3)滴注阿托品（调节松弛）或伊洛卡品（调节痉挛）后，睫状肌束的毛孔变窄。2．通过红外验光计发现了人眼调节的微波动与心脏搏动之间的关系。使用相同的方法，测量近视的调节。结果表明，戴眼镜矫正近视的调节反应比正视眼的调节反应小。

项目成果

Ujiie,Kazuyoshi: The three-dimentional functional structure of the outflow routes.

Ujiie Kazuyoshi：流出通道的三维功能结构。

Tokoro, Takashi: "Accommodatine response in myopia with spectacles" Journal of Ophthalmological Optics Society of Japan. 8. 27-31 (1987)

Tokoro, Takashi：“戴眼镜近视的调节反应”日本眼科光学学会杂志。

Okuyama, Fumio: "Dynamic analysis between accommodation and pupil size of the buman eye - Influence of respiration and pulsation" Journal of Ophthalmological Optics Socicty of Japan (in press. 9. (1988)

奥山文雄：“布曼眼的调节和瞳孔大小之间的动态分析 - 呼吸和脉动的影响”日本眼科光学学会杂志（出版中。9.（1988）

Ujiie, Kazuyoshi: "The three-dimentional funetional structure of the outflow routes"

Ujiie Kazuyoshi：“流出路线的三维功能结构”

所 敬: 日本眼科学会雑誌. 90. 922-927 (1986)

Takashi Tokoro：日本眼科学会杂志 90. 922-927 (1986)。