Strong Solid Bases for Organic Synthesis

有机合成的强固体碱

• 批准号: 10450301
• 负责人: BABA Toshihide
• 金额: $ 4.61万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10450301/
• 关键词: Base catalysis; Strong solid base; Base strength; Organic synthesis; C-C bond formation; Si-C C-C bond formation; アニオン; アニソン; カルボアニオン; カリウムアミド; シリルアセチレン; ノーアルキン

Active sites (centers) of solid-base play important roles of (1) the abstraction of protons from the reactants, (2) activation of reactants without proton abstraction and (3) cooperative action of acidic and basic sites. In present short review, the roles (1) and (2) were focused to understand the catalysis by strong solid-bases such as KNHィイD22ィエD2 on alumina and KF on alumina, respectively. The preparation and characterization of these catalysts were described. To extend utility of the strong solid-base catalysts, they were applied to various reactions including the isomerization of alkenes and alkynes, the dimerization of alkynes, Tishchenko reaction, and the formation of Si-C, Si-N and Si-O bonds.

固体碱基的活性位点（中心）起着（1）反应物的质子抽象的重要作用，（2）无质子抽象的反应物的激活以及（3）酸性和碱性位点的合作作用。在目前的简短综述中，将角色（1）和（2）分别通过强固体碱（例如在氧化铝上的KnHII D22）和氧化铝上的KF理解催化剂。描述了这些催化剂的制备和表征。为了扩展强碱催化剂的效用，它们被应用于各种反应中，包括烷烃和炔烃的异构化，碱的二聚体，Tishchenko反应以及Si-C，Si-C，Si-N和Si-O键的形成。

项目成果

Toshihide Baba, Satoru Hikita, Haruhisa Handa, and Yoshio Ono: "Catalytic Property of Europium Supported on Alumina from Its Ammoniacal Solution"Res. Chem. Intermediates. 24. 495-505 (1998)

Toshihide Baba、Satoru Hikita、Haruhisa Handa 和 Yoshio Ono：“氨溶液中氧化铝负载铕的催化性能”Res。

Toshihide Baba, Hisashi Kizuka, Haruhisa Handa and Yoshio Ono: "Reaction of Ketones or Aldehydes with 1-Alkynes over Solid-Base Catalysts"Appl. Catal. A, Gneral. (in press).

Toshihide Baba、Hisashi Kizuka、Haruhisa Handa 和 Yoshio Ono：“酮或醛与 1-炔烃在固体基催化剂上的反应”应用。

E,Suzuki Y.Ono: "Disproportionation of triethoxysilane over KF/Al_2O_3 and heat-treated hydrotalcite" Applied Catalysis General. 166. 419-424 (1998)

E，Suzuki Y.Ono：“三乙氧基硅烷在 KF/Al_2O_3 和热处理水滑石上的歧化”应用催化综述。

Toshihide Baba, Akiko Kato, Hiroko Yuasa, Fumihiko Toriyama, Haruhisa Handa, and Yoshio Ono: "New Si-C Bond Forming Reactions over Solid-Base Catalysts"Catal. Today. 44. 271-276 (1998)

Toshihide Baba、Akiko Kato、Hiroko Yuasa、Fumihiko Toriyama、Haruhisa Handa 和 Yoshio Ono：“固体基催化剂上的新 Si-C 键形成反应”催化剂。

Toshihide Baba, Akiko Kato, Hiroko Yuasa, Fumihiko Toriyama, Haruhisa Handa, and Yoshio Ono: "Metathesis of Siliylalkynes and Cross-Metathesis of Siliylalkyne and 1-Alkyne over Solid-Base Catalysts"J. Catal.. 176. 488-494 (1998)

Toshihide Baba、Akiko Kato、Hiroko Yuasa、Fumihiko Toriyama、Haruhisa Handa 和 Yoshio Ono：“甲硅烷基炔的复分解以及甲硅烷基炔和 1-炔在固体基催化剂上的交叉复分解”J。