Why the arterial blood pressure increases during exercise? -A role of muscle mechanoreflex-

为什么运动时动脉血压会升高？

基本信息

批准号：
08680117
负责人：
SADAMOTO Tomoko
金额：
$ 1.6万
依托单位：
Graduate School of Human Culture, Nara Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08680117/
关键词：
blood pressure heart rate central command overground locomotion mechanical load change 負荷変化予測教示内容 Locomotion Central descending signal Decerebrate cat カテコールアミン機械的情報反射性制御

项目摘要

EXPERIMENT I. To examine whether the cerebrum is essential for producing the rapid cardiovascular adjustment at the beginning at overground locomotion, we examined heart rate (HR), mean arterial blood pressure (MAP), and integrated electromyogram (iEMG) of the forelimb triceps brachialis muscle during locomotion in freely-moving decerebrate cats. Two to four days after decerebration surgery performed at the level of precollicular-premammillary body, the animals would spontaneously produce overground locomotion supporting body weight. HR began to increase immediately before the onset of iEMG, and MAP began to rise almost simultaneously with the iEMG onset. Their increases in HR and MAP(24 * 3 bpm and 22 * 4 mmHg) were sustained during locomotion. Sinoaortic denervation (SAD) did not affect the abrupt changes in HR and MAP at the beginning of locomotion (0-4 s from the onset of iEMG), whereas SAD had a contrasting effect during the subsequent period, a decrease in the HR response (9 * 1b … More pm) and an increase in the MAP response (30 * 3 mmHg). These results suggest that the cerebrum an the rostral part of the diencephalon are not essential for producing the rapid cardiovascular adjustment at the beginning of spontaneous overground locomotion. The arterial baroreflex does not contribute this rapid adjustment but play an important role in regulating the cardiovascular responses during the later period of spontaneous locomotion.EXPERIMENT II. To examine the role of a sudden load change on the cardiovascular adjustments during the bicycling exercise. Fifteen healthy female volunteers performed the same bicycling exercise which included one abrupt change of load-up or load-down under three different conditions in which the preliminary instructions about the load change given verbally before the bicycling exercise were no, true or false. The true and false instructions both produced anticipatory increases in HR and MAP observed 30 s before the onset of the load change, whereas no instruction did not alter them. After the onset of load-up or load-down, the cardiovascular responses to true instruction were more rapid than to other instructions. These results suggest that preliminary instructive preparation for voluntary exercise could modify the cardiovascular adjustment to the abrupt load changes. Less

实验I.检查在地球上的运动XAMOTION XAMOTION XAMATIEN XAMAINT SEAM RATIE（HR），平均人工血压（MAP）和综合氨基摩肌（IEMG）的近端肌肉（IEMG）的手术中，前肢tricepram brashialis肌肉的肌肉在自由移动期间，是否会产生快速心脏的心脏腔（HR）和集成的氨基摩肌（IEMG）。猫。）在运动开头（从IEMG的发作开始0-4 s）的HR和地图上没有突然变化……更多PM）和MAP响应的增加（30 * 3 mmHg）。在自发的地面运动开始时，息肉对于产生快速的心血管，这并不能使这种快速调整，但在调节心血管响应期间的自发性运动中的心血管响应在骑自行车的骑行过程中，在骑自行车的情况下，洛伦的负载在骑自行车的情况下进行了调整。在载荷变化之前，观察到30 s，而没有指示的矿石速度不快于其他指令。