Functional, anatomical, and neurophysiological study of human upper limb muscles

人体上肢肌肉的功能、解剖学和神经生理学研究

• 批准号: 07670008
• 负责人: NAITO Akira
• 金额: $ 1.54万
• 依托单位: Shinshu University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07670008/
• 关键词: human upper limb muscles; functional electrical stimulation (FES); neuromuscular stimulation data; neural connection; group Ia fibers; synapse; post-stimulus time-histogram (PSTH); motor unit; ヒト肢筋; post-stimulus time-histogrnm(PSTH); ヒト上肢; 多チャ

1.Functional and anatomical studies of the elbow flexors.Forearm supination produced by electrical activation of two elbow flexors (biceps brachii : BB,brachioradialis : BR) was examined in healthy human subjests. The muscles were activated separately by electrical stimulation through wire electrodes with a computer-controlled multi-channel stimulator. Activation of BB induced flexion and supination and that of BR induced flexion. Activation of BR with adequate stimulation intensity provided holding of elbow with maintaining the forearm prone. In this situation, additional activation of BB accompanied with a decrease of stimulation intensity for BR resulted in supination without flexion. Since the triceps brachii showed no contraction throughout the motion, it supports a theory that compensatory changes of activities among the flexors permit BB to work for supination without flexion.2.Neurophysiological studies of the muscles crossing the elbow joint.Neural projections among the biceps brachii (BB), brachioradialis (BR), and pronator teres (PT) in humans were studied using the method of post-stimulus time histograms of voluntarily activated motor units. Electrical conditioning stimuli to the BB,BR and PT nerves resulted in inhibition in motor units of BR and PT,of BB and PT,and of BB,respectively. The inhibition was induced with the stimulation intensity well below the motor threshold. The latency of the inhibition was 0-2ms longer than that of the homonymous facilitation. These findings suggest that inhibitiory projections between BB and BR,and between BB and PT,and from BR to PR exist and the inhibition is mediated through group I afferents and oligo (di or tri) -synaptic linkage.

1.肘屈肌的功能和解剖学研究。在健康人体受试者中检查了通过电激活两个肘屈肌（肱二头肌：BB，肱桡肌：BR）产生的前臂旋后。使用计算机控制的多通道刺激器通过线电极进行电刺激，分别激活肌肉。 BB 的激活引起屈曲和旋后，BR 的激活引起屈曲。以足够的刺激强度激活 BR，可以保持肘部并保持前臂俯卧。在这种情况下，BB 的额外激活伴随着 BR 刺激强度的降低导致旋后而不屈曲。由于肱三头肌在整个运动过程中没有表现出收缩，因此它支持这样一种理论，即屈肌之间活动的代偿性变化允许BB在不屈曲的情况下进行旋后工作。2.穿过肘关节的肌肉的神经生理学研究。肱二头肌之间的神经投射使用自愿刺激后时间直方图的方法研究了人类的肱桡肌 (BB)、肱桡肌 (BR) 和旋前圆肌 (PT)激活的运动单位。对 BB、BR 和 PT 神经的电调节刺激分别导致 BR 和 PT、BB 和 PT 以及 BB 运动单位的抑制。通过远低于运动阈值的刺激强度来诱导抑制。抑制潜伏期比同名促进潜伏期长0-2ms。这些发现表明，BB 和 BR 之间、BB 和 PT 之间以及从 BR 到 PR 之间存在抑制投射，并且抑制是通过 I 组传入神经和寡（二或三）突触连接介导的。

项目成果

Miyasaka T,Sun Y-J,Naito A,Shindo M: "Neural connections between the biceps brachii and the brachioradialis in human." Technical Report of IEICE. MBE96-76. 109-114 (1996)

Miyasaka T、Sun Y-J、Naito A、Shindo M：“人类肱二头肌和肱桡肌之间的神经连接。”

宮坂 卓治: "ヒト上腕二頭筋と腕橈骨筋の間の神経結合について:PSTH法を用いた解析" 信学技報. MBE96-76. 109-114 (1996)

Takuji Miyasaka：“关于人类肱二头肌和肱桡肌之间的神经连接：使用 PSTH 方法进行分析”MBE96-76 (1996)。

Sun Y-J,Miyasaka T,Naito A,Chishima R,Shindo M: "Neural projection from the biceps brachii to the pronator teres in human : and electrophysiological study with a PSTH method." Technical Report of IEICE. MBE96-77. 115-120 (1996)

Sun Y-J、Miyasaka T、Naito A、Chishima R、Shindo M：“人体从肱二头肌到旋前圆肌的神经投射：以及 PSTH 方法的电生理学研究。”

Naito A: "Inhibitory projections from brachioradialis to biceps brachii motoneurones in human." Exp.Brain Res. 111. 483-486 (1996)

Naito A：“人类从肱桡肌到肱二头肌运动神经元的抑制性投射。”

Miyasaka T,Sun Y-J,Chishima R,Naito A: "Inhibitory projections from the biceps brachii to the pronator teres motoneurones in human : an electrophysiological study with a PSTH method" Acta Anat Nippon. 72. 286 (1997)

Miyasaka T、Sun Y-J、Chishima R、Naito A：“人体从肱二头肌到旋前圆肌运动神经元的抑制性投射：采用 PSTH 方法的电生理学研究”Acta Anat Nippon。