宇宙長期滞在模擬の生理的変化を人工重力の遠心負荷で予防出来るか

人造重力的离心载荷能否阻止长期停留在太空所模拟的生理变化？

基本信息

批准号：
07407013
负责人：
YAJIMA Kazuyoshi
金额：
$ 12.16万
依托单位：
Nihon University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1997
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07407013/
关键词：
6 degrees head down tilt stop hematocrit increase short arm human centrifuge artificial gravity long term space flight cardiovascular countermeasure space medicine research 地上での無重量模擬宇宙循環系変化の対策人工重力 6度ヘッドダウン(HDT)2G1時間の遠心負荷短腕遠心機 /

项目摘要

4 days 6 degrees head down tilt bed rest (HDT) experiments were conducted for 10 healthy male students at Nihon University School of Medicine. By a courtesy of Shimizu Co., a 1.8 m radius human centrifuge was set at their Space Development Laboratory and the above mentioned HDT facilitiy was atatched next to the centrifuge room. 10 subjects were kept under a severe control to keep the HDT 24 hours except 15 minutes of secretion and one hour of 2Gz+ centrifugation every day. From many HDT studies up to the present, it has been clear that only hematocrit significantly increases among many physiological changes according to 4 days HDT.No significant increase was observed among the averaged hematocrit values during the 4 days HDT.By other countermeasures as walking arround or standind on the bed (lG load simulation) for up to 2 hours in 4 days HDT, conducted by Convertino et al., hematocrit increase could not be intercepted. This report is the first deta of short arm centrifuge, proving that the centrifugation is more effective than other countermeasures to inhibit the hematocrit increase normally induced in 4 days HDT on the ground. Considering these facts, centrifugation is the first choice to be adopted for artificial gravity in a long term space life, compared with the other countermeasures such as some exercises or other conventional ways to prevent the physiological changes due to the microgravity condition in space.

4天6度倾斜床休息（HDT）实验在Nihon University医学院为10名健康男学生进行了实验。由Shimizu Co.的礼貌，在其太空开发实验室设定了1.8 m半径的离心机，上述高清高清设施旁边是离心室旁边的。除了每天15分钟的分泌和1小时的2Gz+离心15分钟外，将10个受试者保持严重控制，以保持HDT 24小时。从许多HDT研究到现在，很明显，只有4天的HDT在许多生理变化中只有血细胞比容显着增加。或在convertino等人进行的4天HDT中最多2小时的床（LG负载模拟）停留2小时，无法拦截血细胞比容的增加。该报告是短臂离心机的第一个DETA，证明离心比其他对策更有效，可以抑制通常在HDT 4天HDT上抑制血细胞比容的增加。考虑到这些事实，与其他对策（例如某些练习或其他常规方法）相比，离心是人为重力在长期寿命中采用的首选，以防止由于太空中的微重力条件而导致生理变化。