Does the prosthodontic treatment for anodontia cause the neuroplastic change of cerebral cortex activity?

无牙修复治疗是否会引起大脑皮层活动的神经塑性改变？

基本信息

批准号：
16591969
负责人：
NARITA Noriyuki
金额：
$ 2.11万
依托单位：
Nihon University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2006
项目状态：
已结题

项目摘要

From the aspects of neural activation of cerebral cortex accompanying mastication and swallowing, the effects of partial prosthodontic treatment was investigated with NIRS system (Hitachi, ETG 100) and following results were obtained ;1. Using the principal component analysis for brain blood volume, muscle blood could be excluded from NIRS data, Hb mapping and topography were reconstructed with the changing of cerebral blood flow. Activation in the primary sensorimotor and post-parietal and supplementary motor cortices were indicated accompanying with the performance of matication and swallowing.2. Cortical activation of primary sensorimotor cortex, and post-parietal and supplementary motor cortex during mastication were decreased by the injection of anesthesia into infra-alveolar nerve, therefore oral sensation can affect to the cortical sensorimotor function and sensory integration.3. Masticatory loading and masticatory imagery activated the prefrontal cortex, and the focus of its activation was indicted in the bilateral dorsolateral prefrontal cortex areas.4. Cortical activation of prefrontal cortex during mastication was decreased by the injection of anesthesia into infra-alveolar nerve, therefore prefrontal cortex is involved in perception of oral sensory and sensorimotor integration.5. Oral dysesthesia indicated the hypofrontality in the prefrontal cortex comparing with healthy controls, it is therefore assumed that hypofrontality in mastication may reflect to the oral dysesthesia.6. Concerning the effects of prosthodontic treatment to the cortical activation, wearing partial denture more activated the sensorimotor and prefrontal cortices during mastication.It was assumed that the prosthodontic reconstruction of oral apparatus affects to the functional upgrading in the perception of oral sensory, the sensorimotor integration, and the masticatory motor planning and execution.

从伴随咀嚼和吞咽的脑皮质的神经激活方面，通过NIRS系统（Hitachi，ETG 100）研究了部分肢体治疗的作用，并获得了以下结果； 1。使用主要成分分析用于脑血容量，可以从NIRS数据中排除肌肉血液，随着大脑血流的变化，重建了HB映射和地形。指出了乳房和吞咽的性能2。一级感觉运动皮层的皮质激活以及在咀嚼过程中咀嚼过程中的顶质和补充运动皮质的皮质激活通过将麻醉注射到胸腔神经中减少，因此口服感觉会影响皮层感觉运动功能和感觉整合。3。咀嚼载荷和咀嚼图像激活了前额叶皮层，其激活的重点在双侧背外侧前额叶皮层区域被起诉。4。通过将麻醉注射到肺泡神经中，咀嚼过程中额叶皮质的皮质激活减少，因此前额叶皮层参与口服感觉和感觉运动整合的感知。5。口服异常表明前额叶皮层与健康对照组相比，前额叶皮质的性低，因此假定咀嚼性中的低纤维可能反映了口腔感觉障碍。6。关于假肢治疗对皮质激活的影响，戴部分义齿在咀嚼过程中更激活感觉运动和前额叶皮质。是否假定口腔膜的假体重建会影响到功能升级，从而在口腔感觉的感知中升级到功能升级，感知到口腔感官，感觉器整合，感觉器整合，感觉器整合，感觉器整合，感觉器，，感觉良好，，感觉器整合，感知性升级。以及咀嚼电动机计划和执行。