Establishment of evidence-based electrodiagnosis of cervical spondylotic myelopathy

脊髓型颈椎病循证电诊断方法的建立

基本信息

批准号：
14570621
负责人：
SONOO Masahiro
金额：
$ 1.79万
依托单位：
Teikyo University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2002
资助国家：
日本
起止时间：
2002 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570621/
关键词：
cercial spondylosis needle electromyography somatosensory evoked potentials median verve tibial nerve cervical spondylotic myelopathy nerve conduction studies carpal tunnel syndrome

项目摘要

Cervical spondylotic myelopathy (CSM) is popular in Japan but its diagnostic strategy is not well established compared to the cervical spondylotic radiculopathy that is popular in western countries. We aimed to establish the diagnostic strategy of CSM. For this purpose we made researches regarding the following three aspects. 1.To establish the normal values for somatosensoy evoked potentials (SEPs) and nerve conduction studies (NCS). 2.To establish methods of diagnosis and differential diagnosis for diseases that may be confusing with CSM. 3.To collect the needle electromyography (NEE) and SEP data of CSM patients and to establish the diagnostic strategy of CSM.We achieved the following results while supported by this grant. 1.We collected tibial nerve SEP data of 65 control subjects and established normal values considering subject factors, such as height or age. We revealed the origin of N10 component in median nerve SEPs. We found a new pitfall in sensory NCS in lateral antebrachial cutaneous nerve. 2.We found a new pitfall in the orthodromic sensory NCS in CTS, an important differential diagnosis with CSM. We reported the first case in Japan of postmedian sternotomy C8 plexopathy fully utilizing electrodiagnostic method. The head investigator Sonoo discovered a new neurological sign "Sonoo sign ; abductor sign", which is useful in discriminating between organic and non-organic paresis of a leg. We identified the initial lesion of tabes dorsalis using tibial nerve SEPs. 3.We collected EMG data for around 120 CSM cases and are now constructing a database of their EMG findings. We also prospectively recorded median and tibial SEPs for around 50 CSM cases. Analysis of these vast data will take some more time. The head investigator Sonoo wrote many other review articles and delivered many lectures regarding electrodiagnosis of neurological diseases.

颈椎脊髓病（CSM）在日本很受欢迎，但与西方国家流行的宫颈脊柱放射性疾病相比，其诊断策略尚未确定。我们旨在建立CSM的诊断策略。为此，我们对以下三个方面进行了研究。 1.建立体感的诱发电位（SEP）和神经传导研究（NCS）的正常值。 2.建立可能与CSM混淆的疾病的诊断方法和鉴别诊断方法。 3.收集CSM患者的针头肌电图（NEE）和SEP数据，并建立CSM的诊断策略。我们在该赠款支持的同时达到了以下结果。 1.我们收集了65位控制受试者的胫骨神经SEP数据，并在高度或年龄等主题因素（例如身高或年龄）中建立了正常值。我们揭示了中位神经SEP中N10成分的起源。我们发现在侧向毛发皮肤神经中的感觉NC中有一个新的陷阱。 2.我们在CTS中发现了正质感官NC的新陷阱，CTS是CSM的重要差异诊断。我们报道了日本的第一个病例，介导后胸腔切开术C8丛病完全利用电诊断方法。调查员Sonoo发现了一个新的神经系统标志“ Sonoo标志；绑架者标志”，该标志可用于区分腿的有机和非有机瘫痪。我们使用胫骨神经seps鉴定了tabes背心的初始病变。 3.我们收集了大约120个CSM病例的EMG数据，现在正在构建其EMG发现的数据库。我们还未来记录了大约50个CSM病例的中位数和胫骨SEP。对这些庞大数据的分析将需要更多时间。调查员Sonoo撰写了许多其他评论文章，并发表了许多有关神经系统疾病电诊断的讲座。

项目成果

期刊论文数量（136）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Clinical neurophysiological evaluation of patients with severe brain injury.

严重脑损伤患者的临床神经生理学评估。

DOI：
发表时间：
2005
期刊：
Neurological Medicine 62・1
影响因子：
0
作者：
Wakayama Y;Jimi T;Inoue M;et al.;Sasaki S et al.;Sonoo M.;Shibata N et al.;Hatanaka Y et al.
通讯作者：
Hatanaka Y et al.

Isolated index finger palsy

孤立性食指麻痹