A new correction method combined attenuation correction using a difference of intrinsic dual-energy in 201T1C1 SPECT

201T1C1 SPECT中利用本征双能差进行衰减校正的新校正方法

基本信息

批准号：
17591255
负责人：
ONOGUCHI Masahisa
金额：
$ 0.7万
依托单位：
Kanazawa Uiersity
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

项目摘要

We devised a new correction method that combined attenuation correction using a difference of intrinsic dual-energy between lower energy emissions (71keV) and higher energy emissions (167keV) without transmission scan and Compton scatter correction using triple-energy window (TEW) method for 71keV because of enhancing a difference of intrinsic dual-energy in ^<201>TlCl (^<201>Tl), and applied to cardiac phantom and myocardial perfusion SPECT studies.Attenuation coefficients ratio and counts ratio for 71keV/167keV were calculated from SPECT data acquired by energy window of 71keV and 167keV, respectively. Defects with the same thickness were inserted on the inner surface of a myocardial phantom at 2 difference locations: anterior (ANT) and inferior (INF). The myocardial perfusion SPECT studies was performed with ^<201>Tl using the same protocol that we use for patients. The images reconstructed by non-attenuation-scatter (A(-)S(-)), only scatter (A(-)S(+)) and attenuation-scatter (A(+)S … More (+)) correction were compared by visual and quantitative analysis, respectively.The adequate attenuation coefficients ratio and counts ratio for 71keV/167keV were 2.277 and 5, respectively. In the normal myocardial phantom, the INF wall was improved by attenuation-scatter (A(+)S(+)) correction, and the whole of the myocardial wall was uniform.In the ANT and INF defect wall phantom, the tracer distribution except defect wall were uniform, and the all defects were clearly detected. In patients with known or suspected CAD, defect regions were clearly discriminated by technique, the detectability for CAD was improved.It is suggested that a new correction method that combined attenuation correction using a difference of intrinsic dual-energy and Compton scatter correction using triple-energy window (TEW) method for 71keV is useful in ^<201>Tl myocardial perfusion SPECT studies. This may reduce both of attenuation and scatter artifacts, and allow the more accurate assessment of patients with known or suspected CAD. Less

我们设计了一种新的校正方法，该方法结合了使用低能量发射（71keV）和高能量发射（167keV）之间固有双能量差异的衰减校正（无需透射扫描）和使用三能窗（TEW）方法对71keV进行康普顿散射校正由于增强了^<201>TlCl(^<201>Tl)内在双能的差异，应用于心脏模体和心肌灌注SPECT研究。71keV/167keV 的衰减系数比和计数比分别根据 71keV 和 167keV 能量窗口获取的 SPECT 数据计算得出，将相同厚度的缺陷插入心肌模型内表面的两个不同位置：前部（前部）。 ANT)和下(INF)心肌灌注SPECT研究使用与我们使用的相同方案用^ 201 T1进行。通过非衰减散射 (A(-)S(-))、仅散射 (A(-)S(+)) 和衰减散射 (A(+)S … 更多 (+)) 重建的图像。分别通过视觉和定量分析比较校正结果。正常心肌模型中，71keV/167keV的适当衰减系数比和计数比分别为2.277和5。经衰减散射(A(+)S(+))校正，心肌壁得到改善，心肌壁整体均匀。在ANT和INF缺损壁体模中，除缺损壁外示踪剂分布均匀，所有心肌壁均均匀。在已知或疑似CAD的患者中，通过技术可以清楚地区分缺陷区域，提高了CAD的可检测性。提出了一种利用本征双能差值和康普顿差值进行衰减校正相结合的新校正方法。使用三能量窗(TEW)方法进行71keV的散射校正在^ 201 T1心肌灌注SPECT研究中是有用的，这可以减少衰减和散射伪影，并且允许对已知或疑似CAD的患者进行更准确的评估。较少的

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

The simultaneous correction for attenuation and scatter without transmission scan in thallium-201 myocardial perfusion SPECT

铊201心肌灌注SPECT无需透射扫描同时校正衰减和散射

DOI：
发表时间：
2006
期刊：
Eur J Nucl Med Mol Imaging 33
影响因子：
0
作者：
Tanaka;S.;Yamada;M;Kitahara;S.;Higuchi;T.;Honda;K.;Kamijima;K;Yamada;M.;呉勁;Kenichi Nakajima;Masahisa Onoguchi
通讯作者：
Masahisa Onoguchi

^<201>TlCl発生光子の異なった吸収差を利用したSPECTの減弱補正-理論とJISファントムによる基礎的検討-

^<201>利用TlCl产生的光子的不同吸收差异进行SPECT的衰减校正 -使用理论和JIS模型的基础研究-