A new correction method combined attenuation correction using a difference of intrinsic dual-energy in 201T1C1 SPECT

201T1C1 SPECT中利用本征双能差进行衰减校正的新校正方法

基本信息

批准号：
17591255
负责人：
ONOGUCHI Masahisa
金额：
$ 0.7万
依托单位：
Kanazawa Uiersity
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

项目摘要

We devised a new correction method that combined attenuation correction using a difference of intrinsic dual-energy between lower energy emissions (71keV) and higher energy emissions (167keV) without transmission scan and Compton scatter correction using triple-energy window (TEW) method for 71keV because of enhancing a difference of intrinsic dual-energy in ^<201>TlCl (^<201>Tl), and applied to cardiac phantom and myocardial perfusion SPECT studies.Attenuation coefficients ratio and counts ratio for 71keV/167keV were calculated from SPECT data acquired by energy window of 71keV and 167keV, respectively. Defects with the same thickness were inserted on the inner surface of a myocardial phantom at 2 difference locations: anterior (ANT) and inferior (INF). The myocardial perfusion SPECT studies was performed with ^<201>Tl using the same protocol that we use for patients. The images reconstructed by non-attenuation-scatter (A(-)S(-)), only scatter (A(-)S(+)) and attenuation-scatter (A(+)S … More (+)) correction were compared by visual and quantitative analysis, respectively.The adequate attenuation coefficients ratio and counts ratio for 71keV/167keV were 2.277 and 5, respectively. In the normal myocardial phantom, the INF wall was improved by attenuation-scatter (A(+)S(+)) correction, and the whole of the myocardial wall was uniform.In the ANT and INF defect wall phantom, the tracer distribution except defect wall were uniform, and the all defects were clearly detected. In patients with known or suspected CAD, defect regions were clearly discriminated by technique, the detectability for CAD was improved.It is suggested that a new correction method that combined attenuation correction using a difference of intrinsic dual-energy and Compton scatter correction using triple-energy window (TEW) method for 71keV is useful in ^<201>Tl myocardial perfusion SPECT studies. This may reduce both of attenuation and scatter artifacts, and allow the more accurate assessment of patients with known or suspected CAD. Less

我们设计了一种新的校正方法，该方法使用较低的能量排放（71KeV）和较高的能量排放（167KeV）之间的固有双能量差（167KeV）在没有传输扫描和康普顿散射校正的情况下使用三重能量窗口（TEW）进行71KeV的方法结合了衰减校正，因为增强了interiment and interift and interift and interift and interpliept and inteript niptiept and inteript and interpliept and interpliept and interpliept。心脏幻影和心肌灌注SPECT研究。分别从71KeV和167KeV的能量窗口获得的SPECT数据计算出71KeV/167KeV的衰减系数比和计数比。厚度相同的缺陷插入2个差异的心肌幻影的内表面：前（ant）和下（INF）。使用与患者使用的相同方案进行了心肌灌注SPECT研究。分别通过视觉和定量分析比较了通过非侵蚀剂划分（a（ - ）S（ - ））和衰减散布（a（+）S………（+）S ...更多（+））校正的图像，通过视觉和定量分析进行比较。在正常的心肌幻影中，通过衰减筛分（A（+）S（+））校正改善了INF壁，并且整个心肌壁均匀。在ANT和INF INF缺陷壁Phantom中，示踪剂分布壁均均匀，并且所有缺陷都清楚地检测到了所有缺陷。在已知或怀疑CAD的患者中，缺陷区域清楚地被技术区分了，提高了CAD的可检测性。建议一种新的校正方法，该方法使用固有的双能量和Compton散射校正使用三重能量（TEW）窗口（TEW）进行71Kev的方法在 ^<2010> <2010> tl myocardial pects pypept contential pertection使用三重能量（TEW）方法。这可以减少衰减和分散伪影，并允许对已知或怀疑CAD患者进行更准确的评估。较少的

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

The simultaneous correction for attenuation and scatter without transmission scan in thallium-201 myocardial perfusion SPECT

铊201心肌灌注SPECT无需透射扫描同时校正衰减和散射

DOI：
发表时间：
2006
期刊：
Eur J Nucl Med Mol Imaging 33
影响因子：
0
作者：
Tanaka;S.;Yamada;M;Kitahara;S.;Higuchi;T.;Honda;K.;Kamijima;K;Yamada;M.;呉勁;Kenichi Nakajima;Masahisa Onoguchi
通讯作者：
Masahisa Onoguchi

^<201>TlCl発生光子の異なった吸収差を利用したSPECTの減弱補正-心筋ファントムおよび臨床例への応用-

^<201>利用TlCl产生的光子的不同吸收差异进行SPECT的衰减校正-在心肌模型和临床病例中的应用-