New strategy for developing surface-treated functional titanium based on nano-structure and electronic state analyses

基于纳米结构和电子态分析的表面处理功能钛开发新策略

基本信息

批准号：
15592055
负责人：
TANAKA Yasuhiro
金额：
$ 2.3万
依托单位：
Kagawa University (2005)Nagasaki University (2003-2004)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

项目摘要

1.Binding enhancement mechanism of the metal bonded porcelain with the Au sputter-coated titanium was investigated using transmission election microscopy. The deficient layer on the titanium side disappeared by the Au sputter coating. Without the Au coating, titanium atoms is considered to diffuse on the porcelain side through the reaction layer at the fused interface. On the other hand, gold has a strong affinity for titanium, so the gold layer is considered to hinder titanium diffusing into the porcelain and oxygen diffusing into the titanium.2.The results of the electron energy loss spectroscopy (EELS) well explain the fused interface structure and the crystal structure.3.Ion plating is applied to one of titanium surface treatment methods. Ionized titanium was introduced by an electron beam melting and Ar RF plasma. The thickness of the ion-plated titanium film was about 100 nm and the crystal grain size in the film was around less than 10 nm. Cross-sectional TEM observation was performed.4.Acrylic resin rods at about 1 mm in diameter were subjected to the Ti ion plating and we prototyped titanium implants for animal trials. The benefit of this implant is that we've been able to slice the titanium implant with surrounding tissue using microtome. The trial implant was placed into the middle portion of the diaphysis of the left femur in mouse. After 1-4 days operation, immunohistochemistry with fibronectin (FN) antibody was performed. The results suggest that Plasma FN regulates bone formation.

1.利用透射电子显微镜研究了金属结合瓷与溅射镀金钛的结合增强机理。钛侧的缺陷层通过Au溅射涂层消失。在没有金涂层的情况下，钛原子被认为通过熔融界面处的反应层在瓷侧扩散。另一方面，金对钛有很强的亲和力，因此金层被认为阻碍了钛扩散到瓷中和氧扩散到钛中。2.电子能量损失谱(EELS)的结果很好地解释了熔融现象。界面结构和晶体结构。3.离子镀是钛表面处理方法之一。通过电子束熔化和氩射频等离子体引入电离钛。离子镀钛膜的厚度约为100nm，膜中的晶粒尺寸约为小于10nm。进行横截面TEM观察。4.对直径约1mm的丙烯酸树脂棒进行Ti离子镀，并制作了用于动物试验的钛植入物原型。这种植入物的好处是我们能够使用切片机将钛植入物与周围组织一起切片。将试验植入物放置在小鼠左股骨骨干的中部。手术1-4天后，用纤连蛋白（FN）抗体进行免疫组织化学检查。结果表明血浆 FN 调节骨形成。