Study of electromotive forces on metallic restorations and allergic symptoms in the patients of dental-metal-allergy

电动势对牙齿金属过敏患者金属修复体及过敏症状的影响研究

• 批准号: 15592052
• 负责人: HOSOKI Maki
• 金额: $ 1.86万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15592052/
• 关键词: DMA meter; dental-metal-allergy; electromotive forces; 超電力

I.PurposePurpose of this research is to study the electrolysis stability of metallic restorations in the patients of dental-metal-allergy and control subjects. Electromotive forces of metallic restorations were observed in these two groups. Relationship between allergic metals and the electrolysis stability of metallic restorations was also investigated.II.Materials and MethodsTwenty-three dental-metal-allergy suspected patients who visited Department of Fixed Prosthodontics, Tokushima University Hospital from December 2003 to June 2004 were participated in this research project. Twenty-three adult volunteers without sighs and symptoms of dental-metal-allergy were selected for the control group. Informed consents were taken from all subjects before go through the clinical investigations.Intra-oral examinations were done for all subjects and DMA meter (Morita Co., Dental Metal Activity Meter JS2002) was utilized to evaluate the electromotive forces of the metallic restorations of these … More subjects. Patch test that identifies allergic metals was performed for the suspected patient group.III.Results and DiscussionFor the most part of the restorations, DMA meter recorded ‘metastable' electrolysis stability. Then ‘active' restorations are found and a few restorations showed ‘stable' conditions.‘Active' metals were frequently found in amalgam and Ni-Cr alloy restorations, while the most of the platinum alloy and bond-HI-precious alloy restorations showed ‘stable'. Many of other restorations made with gold-silver-palladium alloy, gold alloy, silver alloy and Co-Cr alloy exhibited ‘metastable'.According to patch test investigation, the suspected patients group was divided into dental-metal-allergy group and patch test negative group. Comparison of the electrolysis stability of metallic restorations was done between the dental-metal-allergy group and the control group that consisted of volunteers and patch test negative patients. The ‘active' bond-HI-precious alloy restorations were found in the dental-metal-allergy patients group.Because of the limited number of the patients, we could not evaluate the affect of the metallic restorations stability on their allergic symptoms. Further investigations will be required to clarify the relationship of dental materials and allergy symptoms. Less

一、本研究的目的是研究牙齿金属过敏患者和对照组金属修复体的电解稳定性，观察两组金属修复体的电动势与金属电解稳定性的关系。二、材料与方法 12月以来到德岛大学医院固定修复科就诊的23名疑似牙齿金属过敏患者2003年至2004年6月参与该研究项目的23名成年志愿者被选为对照组，所有受试者在进行临床调查之前均已知情。对所有受试者进行了检查，并使用 DMA 计（Morita Co.，牙科金属活性计 JS2002）来评估这些受试者的金属修复体的电动势。对疑似患者组进行了过敏金属斑贴试验。 三、结果与讨论 对于大部分修复体，DMA 仪记录了“亚稳态”电解稳定性，然后发现了“活跃”修复体，少数修复体显示“稳定”。在汞合金和镍铬合金修复体中经常发现“活性”金属，而大多数铂合金和结合剂-HI-贵重合金修复体在许多其他修复体中表现出“稳定”。其中金银钯合金、金合金、银合金和钴铬合金表现出“亚稳态”。根据斑贴试验调查，将疑似患者组分为牙齿金属过敏组和斑贴试验阴性组。在牙科金属过敏组和由志愿者和斑贴试验阴性患者组成的对照组之间进行了金属修复体的电解稳定性研究，在牙齿金属过敏组和对照组中发现了“活性”键-HI-贵重合金修复体。牙科金属过敏患者组。由于患者数量有限，我们无法评估金属修复体稳定性对其过敏症状的影响，需要进一步研究以阐明牙科材料与过敏症状的关系。