Ausbildung kortikaler Repräsentationen, die der langfristigen perzeptuellen Bahnung (Priming) zugrunde liegen: Die Rolle von Verarbeitungseffizienz, Aufmerksamkeit, neuronaler Selektivität und Markmalsverlust

长期知觉启动背后的皮质表征的形成：处理效率、注意力、神经元选择性和地标损失的作用

• 批准号: 44294592
• 负责人: Professor Dr. Alan Richardson-Klavehn, Ph.D.
• 金额: --
• 依托单位: Klinik für Neurologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2008
• 资助国家: 德国
• 起止时间: 2007-12-31 至 2010-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/44294592?language=en
• 关键词: Ausbildung; kortikaler; Repr; sentationen; die

Priming is an important, sometimes nonconscious, long-term memory function, by which exposure to a stimulus improves the future cognitive processing of that stimulus. Visual perceptual priming is accompanied by decreased neural responses in the ventral visual stream on repetition (retrieval) that have been hypothesized to reflect (1) increased neural processing efficiency, or (2) sharpened neural responding, or (3) loss of neural feature coding. Counterintuitively, priming has now also been linked with neural response decreases in the ventral visual stream on initial exposure (encoding), suggesting (4) that different neural mechanisms may underlie priming-related neural response decreases at encoding and at retrieval, and (5) that top-down attentional factors at encoding may play an important role in the neural basis of priming. Four experiments are proposed that investigate these five hypotheses regarding the neural basis of priming, by explicitly manipulating cognitive processing efficiency, attention, and perceptual feature match between study and test stimuli, using multi-modal measurements of brain activity (fMRI, MEG, EEG) at both encoding and retrieval.

启动是一种重要的、有时是无意识的长期记忆功能，通过它暴露于刺激可以改善该刺激的未来认知处理。视觉感知启动伴随着重复（检索）时腹侧视觉流中神经反应的减少，这被假设反映了（1）神经处理效率提高，或（2）神经反应锐化，或（3）神经特征编码丢失。与直觉相反，启动现在也与初始暴露（编码）时腹侧视觉流中神经反应的减少有关，这表明（4）不同的神经机制可能是编码和检索时与启动相关的神经反应减少的基础，（5）编码时自上而下的注意因素可能在启动的神经基础中发挥重要作用。提出了四个实验，通过使用大脑活动的多模态测量（fMRI、MEG、EEG）明确地操纵认知处理效率、注意力以及学习和测试刺激之间的感知特征匹配，来研究关于启动的神经基础的这五个假设在编码和检索方面。

项目成果

Distinct Frontoparietal Networks Set the Stage for Later Perceptual Identification Priming and Episodic Recognition Memory

独特的额顶网络为后来的知觉识别启动和情景识别记忆奠定了基础

• DOI: 10.1523/jneurosci.0588-10.2010
• 发表时间: 2010
• 期刊: The Journal of Neuroscience
• 作者: Wimber; M.; Heinze; H.
• 通讯作者: H.

The act of remembering : toward an understanding of how we recall the past

记忆的行为：了解我们如何回忆过去

• DOI: 10.1002/9781444328202
• 发表时间: 2010-09-17
• 作者: John H. Mace

Neuroimaging of Human Memory Linking cognitive process to neural systems

人类记忆的神经成像将认知过程与神经系统联系起来

• DOI: 10.1093/acprof:oso/9780199217298.001.0001
• 发表时间: 2009
• 作者: Richardson

Rapid Memory Reactivation Revealed by Oscillatory Entrainment

振荡夹带揭示了快速记忆重新激活

• DOI: 10.1016/j.cub.2012.05.054
• 发表时间: 2012-08-21
• 期刊: Current Biology
• 影响因子: 9.2
• 作者: M. Wimber;A. Maass;T. Staudigl;A. Richardson;S. Hanslmayr
• 通讯作者: S. Hanslmayr

Prefrontal dopamine and the dynamic control of human long-term memory

前额叶多巴胺与人类长期记忆的动态控制

• DOI: 10.1038/tp.2011.15
• 发表时间: 2011-07-05
• 期刊: Translational Psychiatry
• 影响因子: 6.8
• 作者: Wimber M;Schott BH;Wendler F;Seidenbecher CI;Behnisch G;Macharadze T;Bäuml KH;Richardson-Klavehn A
• 通讯作者: Richardson-Klavehn A