Molecular pathophysiology of amyotrophic lateral sclerosis

肌萎缩侧索硬化症的分子病理生理学

• 批准号: 18K07537
• 负责人: Aizawa Hitoshi
• 金额: $ 2.5万
• 依托单位: Tokyo Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18K07537/
• 关键词: 筋萎縮性側索硬化症; ADAR2; Pin 1; TDP-43; 孤発性筋萎縮性側索硬化症; Pin1; nucleoporin; nuclear isomerase Pin1; importin-α4

项目成果

Underlying embolic and pathologic differentiation by cerebral microbleeds in cryptogenic stroke

• DOI: 10.1007/s00415-020-09732-4
• 发表时间: 2020-02-03
• 期刊: JOURNAL OF NEUROLOGY
• 影响因子: 6
• 作者: Kikuno, Muneaki;Ueno, Yuji;Kikuchi, Takahiko
• 通讯作者: Kikuchi, Takahiko

Low-dose statin therapy for intracranial artery stenosis: A single center preliminary study

小剂量他汀类药物治疗颅内动脉狭窄：单中心初步研究

• DOI: 10.1016/j.jns.2021.120075
• 发表时间: 2022
• 期刊: Journal of the Neurological Sciences
• 影响因子: 4.4
• 作者: Aizawa Hitoshi;Taguchi Takeshi;Ido Nobuhiro;Kato Haruhisa;Terashi Hiroo
• 通讯作者: Terashi Hiroo

Impact of the catechol-O-methyltransferase Val158Met polymorphism on the pharmacokinetics of l-dopa and its metabolite 3-O-methyldopa in combination with entacapone

儿茶酚-O-甲基转移酶 Val158Met 多态性对左旋多巴及其代谢物 3-O-甲基多巴联合恩他卡朋药代动力学的影响

• DOI: 10.1007/s00702-020-02267-y
• 发表时间: 2020
• 期刊: Journal of Neural Transmission
• 影响因子: 3.3
• 作者: Yamamoto Joe;Omura Tomohiro;Kasamo Sachiko;Yamamoto Shota;Kawata Masayoshi;Yonezawa Atsushi;Taruno Yosuke;Endo Hisako;Aizawa Hitoshi;Sawamoto Nobukatsu;Matsubara Kazuo;Takahashi Ryosuke;Tasaki Yoshikazu
• 通讯作者: Tasaki Yoshikazu

Analysis of non-invasive gait recording under free-living conditions in patients with Parkinson's disease: relationship with global cognitive function and motor abnormalities.

帕金森病患者自由生活条件下的无创步态记录分析：与整体认知功能和运动异常的关系。

• DOI: 10.1186/s12883-020-01729-w
• 发表时间: 2020
• 期刊: BMC Neurol
• 影响因子: 2.6
• 作者: Terashi H;Taguchi T;Ueta Y;Okubo Y;Mitoma H;Aizawa H.
• 通讯作者: Aizawa H.

Nuclear pore destruction and loss of nuclear TDP-43 in FUS mutation-related amyotrophic lateral sclerosis motor neurons

• DOI: 10.1016/j.jns.2022.120187
• 发表时间: 2022-03-01
• 期刊: JOURNAL OF THE NEUROLOGICAL SCIENCES
• 影响因子: 4.4
• 作者: Aizawa, Hitoshi;Teramoto, Sayaka;Kwak, Shin
• 通讯作者: Kwak, Shin