Real-time precision functional network mapping of the human brain for neurosurgical applications

用于神经外科应用的人脑实时精确功能网络映射

• 批准号: 21K09149
• 负责人: Bagarinao E.
• 金额: $ 2.66万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2021
• 资助国家: 日本
• 起止时间: 2021-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21K09149/
• 关键词: precision mapping; functional connectivity; real-time fMRI; essential tremor; resting state fMRI; human connectome; neurosurgery

For the FY2022, we have scanned 10 more healthy volunteers, completing the MRI scans of all 20 healthy controls. All participants underwent two imaging sessions, about one month apart. Acquired MRI data includes structural T1 MRI data, an hour of resting state functional MRI data, and diffusion-weighted MRI data. Additionally, we have also acquired the MRI data from patients with essential tremor. Preliminary analysis of the acquired datasets from healthy controls have shown that the reliability of the whole-brain FCOR map exhibited an initial rapid increase as more volumes are incorporated into the analysis. With more volumes added, the reliability measure later plateaus suggesting an upper limit to the reliability as well as an optimal number of volumes to achieve this limit. We have also started the analysis of the data from patients with essential tremor. This will be completed in FY2023.

对于2022财年，我们扫描了10名健康志愿者，完成了所有20个健康对照的MRI扫描。所有参与者都进行了两次成像会议，相距大约一个月。获得的MRI数据包括结构性T1 MRI数据，一个小时的静止状态功能MRI数据以及扩散加权MRI数据。此外，我们还从基本震颤患者那里获取了MRI数据。对从健康对照组获得的数据集进行的初步分析表明，随着将更多的体积纳入分析，整个脑FCOR图的可靠性显示出最初的快速增加。随着添加更多的卷，可靠性测量后期的高原表明可靠性上限以及最佳数量的量以达到此限制。我们还开始对具有必要震颤患者的数据进行分析。这将在2023财年完成。

项目成果

Reserve and Maintenance in the Aging Brain: A Longitudinal Study of Healthy Older Adults

• DOI: 10.1523/eneuro.0455-21.2022
• 发表时间: 2022-01-01
• 期刊: ENEURO
• 影响因子: 3.4
• 作者: Bagarinao, Epifanio;Watanabe, Hirohisa;Sobue, Gen
• 通讯作者: Sobue, Gen

Reproducibility of functional connectivity metrics estimated from resting-state functional MRI with differences in days, coils, and global signal regression

• DOI: 10.1007/s12194-022-00670-6
• 发表时间: 2022-08-12
• 期刊: RADIOLOGICAL PHYSICS AND TECHNOLOGY
• 影响因子: 1.6
• 作者: Kato，Sanae;Bagarinao，Epifanio;Sobue，Gen
• 通讯作者: Sobue，Gen

Brain imaging: From functional mapping to mind reading

脑成像：从功能映射到读心术

• 发表时间: 2021
• 作者: 新田雅之;村垣善浩ら;Epifanio Bagarinao
• 通讯作者: Epifanio Bagarinao

Impairments of connector hubs in brain disorders

脑部疾病中连接器枢纽的损伤

• 发表时间: 2023
• 作者: 武藤淳;峯裕;西山悠也;村山和宏;安達一英;長谷川光広;廣瀬雄一;山田茂樹;Epifanio Bagarinao
• 通讯作者: Epifanio Bagarinao

Functional connector hubs in the cerebellum

• DOI: 10.1016/j.neuroimage.2022.119263
• 发表时间: 2022-05-11
• 期刊: NEUROIMAGE
• 影响因子: 5.7
• 作者: Kawabata, Kazuya;Bagarinaob, Epifanio;Sobue, Gen
• 通讯作者: Sobue, Gen