Novel Molecules and Solids Derived from the Cyaphide Ion

源自 Cyaphide 离子的新型分子和固体

• 批准号: 2348777
• 负责人: Jose Goicoechea
• 金额: $ 57.5万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-08-01 至 2027-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2348777&HistoricalAwards=false
• 关键词: Novel; Molecules; Solids; Derived; Cyaphide

With the support of the Chemical Synthesis program in the Division of Chemistry, Professor Jose M. Goicoechea of Indiana University will study a new class of molecules and solids derived from diatomic analogs of cyanide. Cyanide is found across many areas of chemistry, ranging from biological enzyme cofactors to custom-made magnetic materials and catalysts. Cyanide salts are routinely used in applications including bulk chemical synthesis, electroplating, metallurgy, and as fumigants and insecticides. By contrast, the chemistry of the heavier phosphorus- and arsenic-containing ions, the cyaphide and cyarside ions, respectively, is unexplored despite the enormous potential they offer for the synthesis of interesting magnetic materials. This proposal will explore the synthesis of several molecular targets that will offer insight into the electronic structure and properties of these new chemical building blocks. Ultimately, this will prove critical for their use in the design of an entirely new family of molecules and coordination polymers that are currently absent in the chemical literature. Student research training (undergraduates, high school and graduate students) and student mentoring are important components of the project, as is the creation of a public-facing internet educational resource for the project.The scientific goal of this proposal is to develop novel organometallic compounds containing cyaphide (CP) and cyarside (CAs) ligands for the transfer of these functional groups through metathesis and cross-coupling reactions. Proof-of-concept research by the Goicoechea group suggests that such species are isolable, and that reagents containing these new ions can be made to transfer these reactive groups to metal centers using simple salt-metathesis reaction protocols. Obtaining organic and transition metal complexes with these CP and CAs groups will allow for comparisons of their molecular structures and chemical reactivities with analogous complexes containing the more common cyanide (CN) functional group. The experimental components of the project will be complemented with and guided by computational chemistry. With these species in hand, the research team will explore the synthesis of multi-metallic compounds with bridging CP/CAs groups to understand how these ions can be used to enhance magnetic communication between metal centers in oligomeric, polymeric and ultimately two- and three-dimensional extended solids. The synthetic protocols that will be developed will ultimately allow access to a new family of coordination compounds related to Prussian blue, a class of solids that have applications in numerous technologically relevant areas, including magnetism, sensing, catalysis, and energy storage. On a longer time scale, such discoveries are expected to benefit a broad range of researchers, particularly those working in materials science.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学系化学合成项目的支持下，印第安纳大学的 Jose M. Goicoechea 教授将研究源自氰化物双原子类似物的一类新分子和固体。氰化物存在于许多化学领域，从生物酶辅因子到定制的磁性材料和催化剂。氰化物盐通常用于大量化学合成、电镀、冶金以及用作熏蒸剂和杀虫剂。相比之下，较重的含磷离子和含砷离子（分别为氰化物离子和氰化物离子）的化学性质尚未被探索，尽管它们为合成有趣的磁性材料提供了巨大的潜力。该提案将探索几种分子靶标的合成，从而深入了解这些新化学构件的电子结构和特性。最终，这对于它们在设计目前化学文献中不存在的全新分子家族和配位聚合物中的应用至关重要。学生研究培训（本科生、高中生和研究生）和学生指导是该项目的重要组成部分，为该项目创建面向公众的互联网教育资源也是如此。该提案的科学目标是开发新型有机金属化合物含有 cyaphide (CP) 和 cyarside (CAs) 配体，用于通过复分解和交叉偶联反应转移这些官能团。 Goicoechea 小组的概念验证研究表明，此类物质是可分离的，并且可以使用简单的盐复分解反应方案制备含有这些新离子的试剂，将这些反应基团转移到金属中心。 获得具有这些 CP 和 CA 基团的有机和过渡金属配合物将允许将它们的分子结构和化学反应性与含有更常见的氰化物 (CN) 官能团的类似配合物进行比较。该项目的实验部分将得到计算化学的补充和指导。有了这些物质，研究小组将探索具有桥联 CP/CA 基团的多金属化合物的合成，以了解如何使用这些离子来增强低聚物、聚合物以及最终的二元和三元金属中心之间的磁性通信。维度扩展固体。将开发的合成方案最终将允许获得与普鲁士蓝相关的新配位化合物家族，普鲁士蓝是一类在许多技术相关领域具有应用的固体，包括磁性、传感、催化和能源存储。从长远来看，此类发现预计将使广泛的研究人员受益，特别是那些从事材料科学工作的研究人员。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。