Equipment: MRI: Track 1 Acquisition of a fluorescent confocal microscope at Truman State University

设备： MRI：轨道 1 采购杜鲁门州立大学荧光共聚焦显微镜

• 批准号: 2320258
• 负责人: Stephanie Maiden
• 金额: $ 28.35万
• 依托单位: Truman State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-10-01 至 2026-09-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320258&HistoricalAwards=false
• 关键词: Equipment; MRI; Track; Acquisition; fluorescent

An award is made to Truman State University to acquire a fluorescent confocal microscope to enable cutting-edge cell and developmental biology research. Located in Kirksville, Missouri, Truman is a predominantly undergraduate institution and the state’s only public liberal arts and sciences university. Faculty use innovative teaching strategies and high-impact research experiences to train students in the critical thinking and analytical skills they will need to be successful in their careers and communities. Fluorescent confocal microscopy is an essential tool in cell and developmental biology due to its ability to quickly provide optical sections through thick, sometimes living, specimens. The research and teaching using this instrument will train hundreds of students in confocal microscopy, broadly reaching undergraduates majoring in Biology, Chemistry, Biochemistry and Molecular Biology, Health and Exercise Science, and Nursing. Through existing programs at Truman, local K-12 educators and students will also be given the opportunity to learn about and use fluorescent confocal microscopy, increasing the awareness of this powerful instrument. Additional users from a nearby institution will promote further collaborations and contribute to Truman State University’s positive impact on northeast Missouri and the liberal arts and sciences throughout the state. The faculty members conducting this research use five different model organisms to study fundamental cellular and molecular mechanisms governing animal development, respiratory function, and plant:bacteria interactions. Specifically, this project will determine the roles of two genes in the developing embryos of a roundworm, aid in our understanding of the nerve connections in fruit flies, allow a detailed analysis of how the brain controls breathing in rats, determine how bacteria form beneficial relationships with a clover-like plant, and how pesticides affect the growth of beneficial bacteria on alfalfa roots. The highly detailed images obtained by the fluorescent confocal microscope will enable further presentations and research articles by students and faculty and advance scientific knowledge.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

向杜鲁门州立大学颁发了奖励，以获取荧​​光共聚焦显微镜，以实现尖端的细胞和发育生物学研究。杜鲁门（Truman）位于密苏里州柯克斯维尔（Kirksville），是一家主要的本科机构，也是该州唯一的公共文科和科学大学。教师使用创新的教学策略和高影响力的研究经验来培训学生在职业和社区中取得成功所需的批判性思维和分析技能。荧光共聚焦显微镜是细胞和发育生物学的必不可少的工具，因为它能够通过厚，有时是活的标本快速提供光学切片。使用该工具的研究和教学将培训数百名学生进行共聚焦显微镜，广泛地介绍了生物学，化学，生物化学和分子生物学，健康与运动科学以及护理的本科生。通过杜鲁门的现有计划，还将有机会学习和使用荧光共聚焦显微镜，从而提高对这种强大乐器的认识。来自近机构的其他用户将促进进一步的合作，并为杜鲁门州立大学对密苏里州东北部以及全州的文科和科学的积极影响做出贡献。进行这项研究的教职员工使用五种不同的模型生物来研究控制动物发育，呼吸功能和植物的基本细胞和分子机制：细菌相互作用。具体而言，该项目将确定两个基因在round虫的发育胚胎中的作用，有助于我们理解果蝇中的神经连接，从而详细分析大脑如何控制大鼠的呼吸，确定细菌如何与三叶草类植物的有益关系以及农药如何影响杀虫剂在Alfalfalfalfalfalfalfalfa roots上的生长。荧光共聚焦显微镜获得的高度详细的图像将使学生和教职员工以及提高科学知识的进一步演讲和研究文章。该奖项反映了NSF的法定任务，并被认为是通过基金会的智力优点和更广泛的影响来通过评估来获得的支持。