SBIR Phase I: A Soft, Tip-Growing, Self-Deploying Endotracheal Tube that Enables Visualization-Free Intubation

SBIR 第一阶段：一种柔软、尖端生长、自展开的气管插管，可实现无可视化插管

• 批准号: 2305627
• 负责人: David Haggerty
• 金额: $ 27.44万
• 依托单位: VINE MEDICAL, INC.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2305627&HistoricalAwards=false
• 关键词: SBIR; Phase; Soft; Tip; Growing

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a novel technology that actively intubates airway passages while reducing the risks of complications arising from difficult or failed emergency procedures. Such a procedure is often used with patients suffering from trauma, hypoxia, or cardiac arrest. The proposed soft robotic device extends from its tip, imbued with active mechanical intelligence to autonomously navigate the upper airway enabling visualization-free self-deployment. The proposed technology contrasts with current semi-rigid devices, which are pushed from the proximal base of the device by the user. This project aims to improve intubation success rates, reduce complications, and mitigate system-wide costs associated with failed airway management. Furthermore, the technology aims to reduce the navigation and placement skill sets needed to intubate patients, enabling the potential option for field personnel to safely and readily provide airway management. The product aims to capture a portion of the $2 billion annual global airway devices market, ultimately expanding the market through greater user adoption and use case options.This Small Business Innovation Research (SBIR) Phase I project aims to demonstrate proof of concept for a self-deploying intubation device. A soft robotics system will be developed that aims to achieve a 90% first-pass intubation success rate. The technical measures include deploying at an effective pressure (20kPa), in a rapid manner (15s), with comparable forces to the tissue (15N) as expert-guided laryngoscopes, agnostic to user skill sets. During Phase I, design and engineering will be furthered to enable feasibility testing and product validation. The design will be optimized for efficacy, safety, and speed via iterative cadaver testing. Completion of this project will yield an operational, tip-growing, soft robotic prototype for airway intubation accounting for human variability.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项小型企业创新研究（SBIR）I期项目的更广泛的影响/商业潜力是一项新型技术，可积极插管气道通道，同时降低由于困难或失败的紧急程序而引起的并发症风险。 这种程序通常与患有创伤，缺氧或心脏骤停的患者一起使用。拟议的软机器人设备从其尖端延伸，充满主动的机械智能，以自主驾驶上呼吸道，从而无视自我部署。 提出的技术与当前的半刚性设备进行了对比，这些设备被用户从设备的近端底座推动。该项目旨在提高插管成功率，减少并发症并减轻与气道管理失败相关的全系统成本。此外，该技术旨在减少插管患者所需的导航和放置技能集，从而为现场人员提供安全和容易提供气道管理的潜在选择。该产品旨在捕获全球年度全球气道设备市场的一部分，最终通过更大的用户采用和用例选项来扩展市场。这项小型企业创新研究（SBIR）I阶段项目旨在证明自我的概念证明 - 部署插管装置。将开发一个旨在达到90％的第一届插管成功率的软机器人系统。技术措施包括以有效的压力（20KPA）快速部署（15s），与组织（15N）相当的力（15N）作为专家引导的喉镜，对用户技能集的不可知论。在第一阶段，设计和工程将进一步促进可行性测试和产品验证。 该设计将通过迭代尸体测试进行优化，以实现功效，安全性和速度。该项目的完成将产生一个可用于人类可变性的气道插管的操作，提示，软机器人原型。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子和更广泛影响的评估标准的评估来获得支持的。