Planning: ANT LIA Planning an Antarctic Omics Initiative (AOI) to Advance Understanding of the Evolution and Adaptive Potential of Antarctic Organisms
规划:ANT LIA 规划南极组学计划 (AOI),以加深对南极生物进化和适应潜力的了解
基本信息
- 批准号:2231468
- 负责人:
- 金额:$ 14.35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-15 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Life in Antarctica and the Southern Ocean is exceptionally susceptible to climate change. Understanding how Antarctic organisms and assemblages acclimate and adapt to climatic shifts and cascading impacts is essential to conservation efforts and forecasting critical changes. The blueprints of evolutionary history and the potential to adapt to environmental change are encoded in (meta)genomes. This project is a response to the National Academies of Science, Engineering and Medicine’s (NASEM) 2015 Strategic Vision for Antarctic and Southern Ocean Research vision of an Antarctic genomics initiative that would catalyze the science needed to decode the genomic and functional bases of adaptation in changing environments across the spectrum of Antarctic life. The project will convene a workshop to build consensus across a diverse community of life scientists to turn this vision into actionable proposals, and there is significant potential for the community building and planning activities to galvanize an Antarctic ‘Omics Initiative (AOI) that will have considerable impacts on society’s understanding of Antarctic life by engendering predictions of how it may evolve, resist, acclimate, or become susceptible to changes in climate. Societal benefits include engaging the scientific community across multiple disciplines, enhancing the diversity of Antarctic researchers, developing new expertise in Antarctic sciences, and fostering an informed public. The primary aim of this project is to realize the potential for making fundamental advances in understanding polar life and its inextricable links to survival and adaptation across Antarctica’s remarkably diverse ecosystems. The project will facilitate a results-driven workshop to create an implementation plan for making transformative advances in understanding Antarctic biota and assemblages and address large-scale, broad, ecosystem-based questions. They will foster an integrative understanding of biological adaptation to environmental change and the extreme ecosystems found in Antarctica and the Southern Ocean by utilizing cross-ecosystem, interdisciplinary comparative genomic approaches. The open-design workshop will engage researchers with expertise in executing large scale, integrated genomics programs, developing models for training, and engaging the next generation of polar scientists. By addressing these large-scale, broad, ecosystem-based questions, this project aims to build a sustainable, networked, international scientific community and engender ideas to serve as the foundation for an initiative that will accelerate knowledge gain and community building. The project aims to build a sustainable community of scientists by recruiting a diverse, inclusive cohort of participants. The participants will create a summary of contributions to date of ‘omics-inspired studies that have contributed to our understanding of Antarctic evolution and adaptation and synthesize the outcomes of the workshop in a report that will be available to NSF and the scientific community.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
南极和南大洋的生活极易受到气候变化的影响。了解南极的生物和组合如何适应气候变化和级联影响对于保护工作和预测关键变化至关重要。 (元)基因组编码了进化史和适应环境变化的潜力的蓝图。该项目是对国家科学,工程和医学学院(NASEM)2015年南极和南方海洋研究的战略愿景,对南极基因组学倡议的构想,该愿景将催化科学在不断变化环境中对南极生活的环境中的基因组和功能基础进行解码所需的科学。该项目将召集一个研讨会,以在一个潜水员的生活科学家社区建立共识,将这一愿景转化为可行的建议,并且在社区建设和规划活动中有很大的潜力来使南极的“ Omics Initiative(AOI)”(AOI)促进社会对社会对反对意见的理解的影响,从而导致对IT的变化,或者将其抗拒变化,或者会变化,或者将其抗拒变化,或者会变化。社会利益包括跨多个学科的科学界吸引科学界,增强南极研究人员的多样性,在南极科学方面发展新的专业知识,并培养知情的公众。该项目的主要目的是实现潜在的潜力,以理解极地生命及其与南极洲多元化的生态系统的生存和适应的无情联系。该项目将促进一个以结果为导向的研讨会,以创建实施计划,以在理解南极生物群和组合以及解决大规模,广泛的基于生态系统的问题方面做出变革性进步。他们将通过利用跨学科比较基因组方法来促进对环境变化和南方大洋中发现的极端生态系统的综合理解。开放设计的研讨会将使研究人员具有专业知识,以执行大规模,集成的基因组计划,开发培训模型并吸引下一代极地科学家。通过解决这些大规模,广泛的基于生态系统的问题,该项目旨在建立一个可持续的,联网的,国际科学界并引发思想,以作为一项将加速知识收益和社区建设的计划的基础。该项目旨在通过招募多样性,包容的参与者来建立一个可持续的科学家社区。参与者将在一份报告中,将参与我们对南极进化和适应的理解并综合工作室的成果的贡献摘要,这将在NSF和科学界提供。这项奖项可通过评估律师的构成范围,反映了NSF的法律范围,并反映了诚实的支持者的范围。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Alison Murray其他文献
Fulminant hepatic failure resulting from lamivudine-resistant hepatitis B virus in a renal transplant recipient: durable response after orthotopic liver transplantation on adefovir dipivoxil and hepatitis B immune globulin.
肾移植受者中拉米夫定耐药乙型肝炎病毒引起的暴发性肝衰竭:原位肝移植后阿德福韦酯和乙型肝炎免疫球蛋白的持久反应。
- DOI:
10.1097/00007890-199912270-00017 - 发表时间:
1999 - 期刊:
- 影响因子:6.2
- 作者:
Marion G. Peters;Gary G. Singer;Todd K. Howard;Sarah Jacobsmeyer;Xiaofeng Xiong;Craig S. Gibbs;Patrick Lamy;Alison Murray - 通讯作者:
Alison Murray
Editor's Comment and Q&A: Comparison of Twin-block and Dynamax appliances for the treatment of Class II malocclusion in adolescents: A randomized controlled trial
- DOI:
10.1016/j.ajodo.2010.04.002 - 发表时间:
2010-08-01 - 期刊:
- 影响因子:
- 作者:
Badri Thiruvenkatachari;Jonathan Sandler;Alison Murray;Tanya Walsh;Kevin O'Brien - 通讯作者:
Kevin O'Brien
Teaching Colonial History through Film
通过电影教授殖民历史
- DOI:
10.1215/00161071-25-1-41 - 发表时间:
2002 - 期刊:
- 影响因子:0.3
- 作者:
Alison Murray - 通讯作者:
Alison Murray
The Physicality to Mental Health and Mentality of Physical Education: A Complex Spiral
体育对心理健康和心态的影响:一个复杂的螺旋
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
Alison Murray;Sarah Adams - 通讯作者:
Sarah Adams
Multiple Sequence Alignment using Fuzzy Logic
使用模糊逻辑的多序列比对
- DOI:
- 发表时间:
2007 - 期刊:
- 影响因子:0
- 作者:
S. Nasser;G. Vert;M. Nicolescu;Alison Murray - 通讯作者:
Alison Murray
Alison Murray的其他文献
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{{ truncateString('Alison Murray', 18)}}的其他基金
Early-life origins of brain resilience to mental illness and cognitive impairment across the life-course
整个生命过程中大脑对精神疾病和认知障碍的恢复能力的早期起源
- 批准号:
MC_PC_MR/R019541/1 - 财政年份:2018
- 资助金额:
$ 14.35万 - 项目类别:
Research Grant
RAPID: Assessing Winter Bacterioplankton Distributions and Carbon Cycling as part of AMLR Field Program, August 2012
RAPID:评估冬季浮游细菌分布和碳循环,作为 AMLR 实地计划的一部分,2012 年 8 月
- 批准号:
1250091 - 财政年份:2012
- 资助金额:
$ 14.35万 - 项目类别:
Standard Grant
Collaborative Research: Geochemistry and Microbiology of the Extreme Aquatic Environment in Lake Vida, East Antarctica
合作研究:东南极洲维达湖极端水生环境的地球化学和微生物学
- 批准号:
0739681 - 财政年份:2009
- 资助金额:
$ 14.35万 - 项目类别:
Standard Grant
IPY: Bacterioplankton Genomic Adaptations to Antarctic Winter
IPY:浮游细菌对南极冬季的基因组适应
- 批准号:
0632389 - 财政年份:2007
- 资助金额:
$ 14.35万 - 项目类别:
Standard Grant
Collaborative Research: Free-Drifting Icebergs as Proliferating Dispersion Sites of Iron Enrichment, Organic Carbon Production and Export in the Southern Ocean
合作研究:自由漂流冰山作为南大洋铁富集、有机碳生产和出口扩散的场所
- 批准号:
0636543 - 财政年份:2007
- 资助金额:
$ 14.35万 - 项目类别:
Continuing Grant
Gene Expression in Extreme Environments: Extending Microarray Technology to Understand Life at its Limits.
极端环境中的基因表达:扩展微阵列技术以了解生命的极限。
- 批准号:
0085435 - 财政年份:2001
- 资助金额:
$ 14.35万 - 项目类别:
Standard Grant
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