Collaborative Research: Assessing the bioethical impacts of an Indigenous scholars network in genomics

合作研究：评估基因组学领域土著学者网络的生物伦理影响

• 批准号: 2124995
• 负责人: Matthew Anderson
• 金额: $ 24.69万
• 依托单位: Ohio State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-10-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2124995&HistoricalAwards=false
• 关键词: Collaborative; Research; Assessing; bioethical; impacts; Collaborative; Research; Assessing; bioethical; impacts

Engagement of Indigenous communities by scientific researchers is riddled with examples of scientific misconduct and a lack of direct benefit to participants and their communities. The Summer internship for INdigenous peoples in Genomics (SING) short course offers training and tools for early career Indigenous scientists to engage in the research process and community members to guide their communities in making informed decisions about research. Alumni of SING and affiliated faculty have organized through the workshop to present ethical concerns around current frameworks of scientific engagement to the general scientific community and to raise the collective voice of Indigenous people in genomics research. However, the impact of SING in its mission to inform participants in genomics research in Indigenous communities and build out networks of collaborating Indigenous researchers have not been explicitly tested. This study defines the role and impact of SING in shaping views of research and incorporatingIndigenous researchers into scholarly networks among Indigenous alumni and faculty. Long-term assessment of training programs such as SING have not been investigated to any great extent such that this can serve as a model for determining the effectiveness of short course scientific training programs.Recognizing that genomic research is inherent in future medical, scientific, and translational research, the inclusion and involvement of Indigenous people is important and the role of SING to facilitate this engagement is unparalleled. In this project, the investigators objectively measure the impact of the SING program by eliciting the perceptions and understandings of genome science and ethics engagement of past SING participants and faculty through focus groups surveys, and social network analysis. Specifically, the project engages SING alumni and participants by 1) elucidating Indigenous perspectives on genetic research and scholarship, 2) defining interactions and influences initiated by SING among Indigenous genomics scholars, and 3) developing and delivering topic specific training for the general public and SING alumni. Findings from this work will inform in-person training for the SING program and engagement of the general scientific community to impact research approaches, scholarship, and public policy.This project was funded through the ER2 program by the BIO directorate.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

科学研究人员对土著社区的互动充斥着科学不当行为的例子，并且对参与者及其社区缺乏直接利益。基因组学土著人民（SING）的暑期实习为早期职业生涯的土著科学家提供培训和工具，以参与研究过程和社区成员，以指导其社区做出有关研究的明智决定。辛格和附属教师的校友通过研讨会组织了围绕一般科学界的科学参与框架提出道德问题，并提高了基因组学研究中土著人民的集体语态。但是，Sing在其使命中的影响是告知土著社区基因组学研究的参与者，并建立了合作的土著研究人员的网络，尚未明确测试。这项研究定义了唱歌在塑造研究观点中的作用和影响，并将无数研究人员纳入土著校友和教职员工之间的学术网络。尚未在很大程度上对诸如唱歌的培训计划（例如唱歌）进行的长期评估，因此可以作为确定短期课程科学培训计划的有效性的模型。认识到基因组研究在未来的医学，科学和翻译研究中是固有的，对本土人员的融合和参与是唱歌的重要和作用，并且是唱歌的重要作用。在该项目中，研究人员通过引起对过去的唱歌参与者和教师通过焦点小组调查以及社交网络分析的基因组科学和道德参与的看法和理解来客观地衡量Sing计划的影响。具体而言，该项目通过1）阐明对遗传研究和奖学金的土著观点，2）定义Sing在土著基因组学者中发起的相互作用和影响的土著观点，以及3）3）开发和提供主题的特定主题培训，为普通公众和Sing Alumni。这项工作的发现将为SIN计划和一般科学界的亲自培训提供信息，以影响研究方法，奖学金和公共政策。该项目是通过Bio Director的ER2计划资助的。该奖项反映了NSF的法定任务，并认为通过基金会的知识分子优点和广泛的影响来评估NSF的法定任务。