Collaborative Research: Identification of Lignin-derived Ligands Associating With Iron

合作研究：鉴定与铁结合的木质素衍生配体

• 批准号: 2108270
• 负责人: Yu Yang
• 金额: $ 22.5万
• 依托单位: Board of Regents, NSHE, obo University of Nevada, Reno
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2108270&HistoricalAwards=false
• 关键词: Collaborative; Research; Identification; Lignin; derived

With support from the Environmental Chemical Sciences Program of the NSF Division of Chemistry, Yu Yang of the University of Nevada, Reno and Rene Boiteau of Oregon State University are studying iron complexes derived from lignin-based organic compounds. Iron oxide-associated organic carbon is one of the largest reservoirs of carbon on the Earth’s surface. Predicting changes to the size of soil carbon reservoirs and sustainably managing soil and water quality is an important challenge. A rigorous understanding of the chemical nature of iron-organic carbon complexes has the potential to assist scientists in this endeavor. So far, the origin and formation mechanism of soil organic carbon in complex with iron remain poorly understood. As a primary precursor for soil organic carbon, plant-derived lignin can be degraded into compounds that may bind to iron oxides. This project aims to uncover the chemical nature of lignin-derived ligands for iron. Soil carbon is an important part of the Earth's carbon cycle, and an element of this cycle that is highly relevant to climate. Graduate, undergraduate, and K-12 students will be engaged in this research at both institutions. Leveraging an NSF-funded Innovations in Graduate Education project, a summer camp module will be developed focusing on environmental chemistry relevant to sustainability, to increase the representation of first-generation students and underrepresented groups in graduate studies in science. This project sets out to develop targeted and non-targeted methods to detect and quantify lignin-derived ligands and their iron complexes by liquid chromatography together with high resolution electrospray ionization mass spectrometry and inductively coupled plasma mass spectrometry. The method will be developed and validated with a set of known lignin degradation products and used to characterize the iron-binding products formed by microbial degradation of lignin in pure culture and soil incubation. It is expected that these studies will help elucidate the chemical nature of biopolymer (lignin)-derived iron ligands and their complexes and provide insights into the chemical mechanisms that fractionate soil organic carbon, ultimately governing soil organic carbon stocks. Such understanding is critical for developing predictive models for the nature and form of soil-constrained organic carbon. The methods developed in this project are expected to be broadly applicable for the investigation of other biopolymer (cellulose, cutin, and others)-derived ligands in soil and aqueous environments.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在NSF化学部的环境化学科学计划的支持下，内华达大学的Yu Yug Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu Yu of Reno和Rene Boiteau的俄勒冈州立大学的Rene Boiteau正在研究源自基于木质素的有机化合物的铁综合体。与氧化铁相关的有机碳是地球表面最大的碳储层之一。预测土壤碳储层的大小以及可持续管理土壤和水质的变化是一个重要的挑战。对铁有机碳配合物的化学性质的理解有可能协助科学家进行这项工作。到目前为止，与铁配合物中土壤有机碳的起源和形成机理仍然了解不足。作为土壤有机碳的主要先驱，植物来源的木质素可以降解为可能与铁氧化铁结合的化合物。该项目旨在揭示木质素衍生的铁的化学性质。土壤碳是地球碳循环的重要组成部分，也是与气候高度相关的该循环的元素。研究生，本科和K-12学生将在这两个机构从事这项研究。利用NSF资助的研究生教育项目的创新，将开发一个夏令营模块，重点关注与可持续性相关的环境化学，以增加第一代学生和科学研究生研究中代表性不足的群体的代表。该项目旨在开发针对靶向和非目标的方法，以通过液相色谱法以及高分辨率电动电离电离质谱法检测和量化木质素衍生的配体及其铁络合物，并通过电感耦合等离子体质谱法。该方法将通过一组已知的木质素降解产物进行开发和验证，并用于表征木质素在纯培养和土壤孵育中形成的铁结合产物。预计这些研究将有助于阐明生物聚合物（木质素）衍生的铁配体的化学性质及其络合物，并提供对分馏土壤有机碳的化学机制的见解，最终导致土壤有机碳储备。这种理解对于为土壤受限的有机碳的性质和形式开发预测模型至关重要。预计该项目中开发的方法将广泛适用于其他生物聚合物（纤维素，切蛋白等）在土壤和水性环境中衍生的配体的投资。该奖项反映了NSF的法定任务，并被认为是通过基金会的知识分子和更广泛影响的评估来审查Criteria，通过评估来通过评估来获得支持。

项目成果

Modeling the fate of ionizable pharmaceutical and personal care products (iPPCPs) in soil-plant systems: pH and speciation

模拟可电离药品和个人护理产品 (iPPCP) 在土壤-植物系统中的命运：pH 值和形态

• DOI: 10.1016/j.envpol.2022.120367
• 发表时间: 2022
• 期刊: Environmental Pollution
• 影响因子: 8.9
• 作者: Shahriar, Abrar;Hanigan, David;Verburg, Paul;Pagilla, Krishna;Yang, Yu
• 通讯作者: Yang, Yu