MRI: Acquisition of Nano-resolution Zeiss Xradia 620 Versa X-ray Computed Tomography with Phase Contrast and Lab Diffraction Contrast Tomography

MRI：获取纳米分辨率 Zeiss Xradia 620 Versa X 射线计算机断层扫描（相衬）和实验室衍射对比断层扫描

• 批准号: 2017977
• 负责人: Amanda Krause
• 金额: $ 120.28万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2017977&HistoricalAwards=false
• 关键词: MRI; Acquisition; Nano; resolution; Zeiss; MRI; Acquisition; Nano; resolution; Zeiss

This award from the Major Research Instrumentation Program supports the acquisition of a Zeiss Xradia 620 Versa Computed Tomography (Versa nanoCT) system at the University of Florida, where it will be accessible to students, researchers, industrial partners, and museum personnel. The Versa nanoCT is a non-destructive characterization tool that provides nano-scale 3D imaging of internal and external features of organic and inorganic specimens. The equipment’s versatility allows it to impact a variety of scientific fields, including materials science, vertebrate zoology, and biomedical engineering. The acquired data will be shared through open source networks and field-specific databases to reach researchers around the world and enable broad-scale data research initiatives. Additionally, the data collected will be implemented in graduate, undergraduate, and high-school education, 3D machine learning development, and public engagement activities via virtual museum collections.The acquisition of a Zeiss Xradia 620 Versa Computed Tomography (Versa nanoCT) system introduces new research opportunities by providing nondestructive, 3D imaging that is essential for identifying critical microstructural or morphological features to fundamental material or biological processes, respectively. Additionally, the unique features of the Versa nanoCT, including the high X-ray source flux, 40X magnification optics, diffraction contrast tomography (LabDCT) and phase contrast, provide essential information that are typically unavailable outside of synchrotron facilities. The Versa nanoCT enables and supports research in three critical areas: (1) elucidating fundamental microstructure-property relationships to control the strength of structural metals and ceramics, (2) archiving morphological diversity to better understand the processes that drive the diversification of living and extinct organisms, and (3) monitoring cell-material interactions to guide tissue generation. The instrument also supports educational initiatives at the graduate, undergraduate, and high-school level, support data support for 3D machine learning initiatives, and engage the public through outreach at the Florida Museum of Natural History (FLMNH) Education and Exhibition Center.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项的主要研究仪器计划的奖项支持在佛罗里达大学获得Zeiss Xradia 620 Versa Compure层析成像（Versa Nanoct）系统，在那里学生，研究人员，工业合作伙伴和博物馆人员都可以访问它。 Versa Nanoct是一种非破坏性表征工具，可为有机和无机标本的内部和外部特征提供纳米尺度的3D成像。该设备的多功能性使其能够影响各种科学领域，包括材料科学，脊椎动物动物学和生物医学工程。获取的数据将通过开源网络和特定于现场的数据库共享，以吸引全球研究人员，并启用大规模的数据研究计划。 Additionally, the data collected will be implemented in graduate, undergraduate, and high-school education, 3D machine learning development, and public engagement activities via virtual museum collections.The acquisition of a Zeiss Xradia 620 Versa Computed Tomography (Versa nanoCT) system introduces new research opportunities by providing nondestructive, 3D imaging that is essential for identifying critical microstructural or morphological features to fundamental material or生物过程分别。此外，Versa Nanoct的独特特征，包括高X射线源通量，40倍放大光学元件，衍射对比度层析成像（LABDCT）和相位对比度，提供了基本信息，这些信息通常在同步器设施以外不可用。 Versa Nanoct可以在三个关键领域提供并支持研究：（1）阐明基本的微观结构 - 性关系，以控制结构金属和陶瓷的强度，（2）归档形态多样性以更好地了解驱动生物和生物生物的多样化的过程，以及（3）（3）监测细胞分泌的互动以指导细胞生物的相互作用。 The instrument also supports educational initiatives at the graduate, undergraduate, and high-school level, support data support for 3D machine learning initiatives, and engage the public through outreach at the Florida Museum of Natural History (FLMNH) Education and Exhibition Center.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using The Foundation's intellectual merit and broader impacts review criteria.