Berry College MRI: Aquisition of a Flex Real-Time PCR System for Undergraduate Research and Teaching

贝里学院 MRI：为本科生研究和教学购置 Flex 实时 PCR 系统

基本信息

批准号：
1828540
负责人：
Angela Poole
金额：
$ 9.96万
依托单位：
Berry College
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2018
资助国家：
美国
起止时间：
2018-10-01 至 2021-09-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828540&HistoricalAwards=false
关键词：
Berry College MRI Aquisition Flex

项目摘要

An award is made to Berry College to increase the research productivity of faculty and enhance undergraduate research and teaching through the acquisition of an Applied Biosystems QuantStudio 7 Flex Real-Time PCR system. Over the three-year grant period, the QuantStudio 7 will enable faculty to engage an estimated 77 undergraduate research assistants and 312 undergraduates in coursework, teaching them modern molecular techniques and comprehensively preparing them for graduate school and careers in science. This instrument will create opportunities for undertaking new laboratory exercises and engaging in research within the classroom in a diverse set of courses, including Molecular Biology, Developmental Biology, Genetics of Domesticated Animals, and Chromatin, Epigenetics, and Gene Expression. The QuantStudio 7 will also facilitate partnerships between Berry and other institutions, including Dalton State College (an HSI) and Colorado State University. In partnership with Armuchee High School (serving economically diverse students) and the Georgia Governor's Honors Program (a summer program held on the Berry campus that serves Georgia's top science students from diverse backgrounds), Berry will provide an estimated 348 high school students with early exposure to molecular research instrumentation and methods, which will help build their confidence in their ability to pursue STEM majors and careers. Given the impact of Berry's activities using the QuantStudio 7, as well as the research and training planned by shared users in the Northwest Georgia region, this instrument will play a role in producing the qualified STEM workers the state needs to meet projected STEM employment growth. It will also further Berry's strategic goal to graduate students who are "life ready" prepared to be agents of improvement through the integration of rigorous academic learning with meaningful applied learning experiences and a heart for service. The QuantStudio 7 will foster and facilitate the OneHealth approach to research, i.e., transdisciplinary collaborations between physicians, veterinarians, epidemiologists, ecologists, climatologists, medical researchers, and numerous other specialties, as dictated by the specific problem being studied. In the immediate future, the QuantStudio 7 will bring together the project's four PIs a diverse group that includes three early-career investigators and other faculty who collectively are studying coral reef ecosystem health, wildlife and domesticated animal health, and parasites related to human health. With access to a modern real-time PCR system, the PIs' research will advance understanding of a broad spectrum of molecular mechanisms. Specifically, the PIs will use the instrument to study potential immune genes and endocrine disruption in cnidarians to better understand how these organisms respond to a changing environment; develop an ideal method for cryopreserving eggs, sperm, and embryos of goat and deer species for agricultural purposes and wildlife conservation; and determine how genetic variants affect early pregnancy and thus facilitate genetic selection programs to improve cow fertility. The PIs will disseminate their research findings through submission of papers to peer-reviewed journals and presentations at national and international meetings. Overall, the QuantStudio 7's robust capabilities will advance future investigations in interconnections between human, animal, and environmental health.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

通过获取Applied Biosystems QuantStudio 7 Flex实时PCR系统，通过授予贝瑞学院的奖励，以提高教师的研究生产力，并增强本科研究和教学。在三年的赠款期内，QuantStudio 7将使教师能够在课程中与大约77名本科研究助理和312名本科生互动，教给他们现代分子技术，并为他们全面为科学研究生和职业做好准备。该工具将创造机会进行新的实验室练习，并在课堂内进行多种课程，包括分子生物学，发育生物学，驯养动物的遗传学以及染色质，表观遗传学和基因表达。 QuantStudio 7还将促进浆果与其他机构之间的合作伙伴关系，包括道尔顿州立大学（AN HSI）和科罗拉多州立大学。与Armuchee高中（经济多样化的学生）和佐治亚州州长的荣誉计划（在贝里校园举行的夏季计划，为乔治亚州的顶级科学专业的学生提供来自不同背景的夏季计划），贝里将提供348名高中学生，以提供348名高中生，分子研究工具和方法，这将有助于建立他们对追求STEM专业和职业能力的信心。鉴于贝瑞使用QuantStudio 7的活动以及佐治亚州西北地区共享用户计划的研究和培训的影响，该工具将在培养国家所需的合格STEM工人方面发挥作用，以满足预计的STEM就业增长。这也将进一步进一步贝瑞（Berry）的战略目标，即“准备好生命”的研究生准备通过将严格的学术学习与有意义的应用学习经验和服务的心脏结合在一起来改进的推动者。 QuantStudio 7将促进和促进研究研究方法，即医师，兽医，流行病学家，生态学家，气候学家，医学研究人员和许多其他专业之间的跨学科合作，如所研究的具体问题所决定的那样。在不久的将来，QuantStudio 7将汇集该项目的四个PIS一个多元化群体，其中包括三个早期职业研究人员和其他教师，他们集体研究珊瑚礁生态系统健康，野生动物和驯养的动物健康以及与人类健康有关的寄生虫。借助现代实时PCR系统，PIS的研究将提高对各种分子机制的理解。具体而言，PIS将使用该工具来研究Cnidarians中潜在的免疫基因和内分泌干扰，以更好地了解这些生物如何对环境变化的反应；为农业目的和野生动植物保护，开发一种理想的方法，用于山羊和鹿种的冷冻鸡蛋，精子和胚胎；并确定遗传变异如何影响早期妊娠，从而促进遗传选择计划以改善牛的生育能力。 PI将通过在国家和国际会议上向同行评审的期刊和演讲提交论文来传播他们的研究结果。总体而言，QuantStudio 7的强大功能将在人，动物和环境健康之间进行未来的调查。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子和更广泛影响的评估评估标准的评估值得支持的。