I-Corps: Low-complexity Asynchronous Re-sampler for Optical Coherence Tomography

I-Corps：用于光学相干断层扫描的低复杂度异步重采样器

• 批准号: 1760126
• 负责人: Sebastian Hoyos
• 金额: $ 5万
• 依托单位: Texas A&M Engineering Experiment Station
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-11-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1760126&HistoricalAwards=false
• 关键词: Corps; Low; complexity; Asynchronous; Re

The broader impact/commercial potential of this I-Corps project is based on significant improvements in accuracy and cost reduction of eye-related disease diagnosis by providing a high-quality, high-speed tissue imaging solution. Specifically, the project will shorten clinical scan time, and as a result, increase image resolution while reducing the number of required patient clinic visits. These improvements directly lower associated medical costs. The project goal is to create a new-generation of Optical Coherence Tomography (OCT), a technique that is used in the clinical practice to provide cross-sectional images of the retina. Currently, the biggest challenge faced by OCT clinical applications is their slow scan speed, which leads to low image resolutions and therefore unsatisfying clinical experience. A high-quality, high-speed signal processing tool is needed for reliable clinical decision-making and disease monitoring with OCT systems.This I-Corps project will further develop a new-generation of Optical Coherence Tomography (OCT). The I-Corps project will explore the commercial potential of the innovation, a system capable of decreasing the signal processing time of swept source OCT (SS-OCT) devices by up to ten times according to lab tests. This device is based on a family of novel signal processing algorithms that significantly improve the accuracy and speed required for the medical images to be acquired. The SS-OCT platform will be enhanced in terms of the image acquisition speed, accuracy, and cost. This, in turn, will decrease the number of visits a patient needs to make to an ophthalmology clinic while increasing the overall clinic capacity to attend visiting patients per day, generating more revenue for those centers.

该I-Corps项目的更广泛的影响/商业潜力是基于通过提供高质量的高速组织成像解决方案来显着提高眼睛相关疾病诊断的准确性和成本降低。具体而言，该项目将缩短临床扫描时间，因此，在减少所需的患者诊所就诊次数的同时，增加了图像分辨率。这些改进直接降低了相关的医疗费用。项目目标是创建新一代的光学相干断层扫描（OCT），该技术用于临床实践中，用于提供视网膜的横截面图像。 目前，OCT临床应用面临的最大挑战是它们的缓慢扫描速度，这导致图像分辨率低，因此不满意的临床经验。使用OCT系统可靠的临床决策和疾病监测需要高质量的高速信号处理工具。这项I-Corps项目将进一步开发出新一代的光学相干断层扫描（OCT）。 I-Corps项目将探索创新的商业潜力，该系统能够根据实验室测试将扫描源OCT（SS-OCT）设备的信号处理时间最多减少十倍。该设备基于一种新型信号处理算法，可显着提高获得医疗图像所需的准确性和速度。 SS-OCT平台将根据图像采集速度，准确性和成本来增强。反过来，这将减少患者对眼科诊所需要进行的就诊次数，同时增加每天参加来访患者的总诊所能力，从而为这些中心带来更多收入。