MRI: Acquisition of Prisma 3T MRI Upgrade

MRI：购买 Prisma 3T MRI 升级版

• 批准号: 1726431
• 负责人: Ashley VanMeter
• 金额: $ 105.27万
• 依托单位: Georgetown University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2017-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1726431&HistoricalAwards=false
• 关键词: MRI; Acquisition; Prisma; 3T; Upgrade

This award provides a substantial upgrade to Georgetown University's 3 Tesla Siemens MRI scanner, which supports the innovative neuroimaging research conducted by 37 researchers from 8 different institutions in the region including (Georgetown University, Catholic University, Children's National Medical Center, Gallaudet University, George Washington University, American University, National Rehabilitation Hospital, and the Veterans Administration). This upgrade will increase the quality of the images acquired and allow the researchers using this scanner to make use of the latest developments in MRI pulse sequences notably those developed for the Human Connectome Project, which will provide better temporal resolution for studies of brain function, better spatial resolution including greater precision with regards to subtle differences in axonal connectivity, and better estimation of metabolite concentration via magnetic resonance spectroscopy (MRS). These improvements will support not only the various researchers but also provide educational opportunities for high school, undergraduate, and graduate students from across the greater Washington, DC metro region that encompasses a diverse ethnic and socioeconomic population.Researchers from 8 different institutions in the greater Washington, DC metro region conduct a wide variety of neuroimaging research using the Siemens Magnetom Tim 3T MRI scanner at Georgetown University. One area of research focuses on neurodevelopment with studies examining reward processing, executive function, autism, reading and math difficulties, and spatial and creative relational reasoning. Another area of research uses this scanner to better understand basic neurological processes related to visual attention, spatial/object-based selection, somatosensory learning and cross-modal integration, sensory cortical organization, and cross-modal plasticity in blind individuals. The Siemens Prisma upgrade significantly increases the capabilities of this facility by providing two new radio frequency head coils, a 32- and 64-channel, that greatly increase the signal-to-noise ratio (SNR) as well as allow for greater scanning parallelization. With the boost in SNR afforded by this upgrade, investigators will have greater flexibility in their functional MRI paradigms with higher spatial and temporal resolution. In addition, the ability to use the Human Connectome Project pulse sequences will greatly improve the power to detect subtle neuroanatomic differences using voxel-based morphometry (VBM) and diffusion tensor imaging (DTI).

该奖项为乔治敦大学的3个特斯拉·西门子MRI扫描仪提供了实质性升级，该奖项支持该地区的37名研究人员进行的创新神经影像学研究，包括（乔治敦大学，天主教大学，天主教大学，乔治大学，儿童国家医学中心，Gallaudton University，American Rehabs Antival Rehaptans，National Rehablant Indersation，National Rehablitant Advistration）。此升级将提高所获取的图像质量，并允许研究人员使用该扫描仪使用MRI Pulse序列中的最新进展，尤其是为人类连接组项目开发的图像序列，这将为脑功能研究提供更好的时间分辨率，更好的空间分辨率，包括在轴突连接性方面具有更高的精度，以及通过轴突连通性的差异和更好的估计来估计MR的MREMPANE RESANES MREPECTERANCE（MR）。这些改进将不仅为各种研究人员提供支持，还将为来自大华盛顿特区大都市地区的高中，本科和研究生提供教育机会，涵盖了多样化的种族和社会经济人口。来自华盛顿州大华盛顿特区的8个不同机构的研究人员使用DC Metro地区的Neuroimimimimimimimimimimimimenging研究员使用了各种各样的研究员，该研究人员使用了各种各样的研究员，使用了各种各样的研究。一个研究领域的重点是通过研究奖励处理，执行功能，自闭症，阅读和数学困难以及空间和创造性的关系推理的研究。另一个研究领域使用该扫描仪更好地了解与视觉关注，基于空间/对象的选择，体感学习和跨模式整合，感觉皮质组织以及盲人中的跨模式可塑性有关的基本神经系统过程。西门子Prisma通过提供两个新的射频头线线圈（32和64通道）可显着提高该设施的功能，从而大大增加了信噪比（SNR），并允许更大的扫描并行化。随着该升级提供的SNR的提升，研究人员的功能MRI范式具有更大的灵活性，并具有较高的空间和时间分辨率。此外，使用人类连接组项目脉冲序列的能力将大大提高使用基于体素的形态计量学（VBM）和扩散张量张量成像（DTI）检测细微神经解剖学差异的功率。