UNS: Collaborative Research: Effects of Nano-Bio Interactions on Nanoparticle Fate and Transport in Porous Media

UNS：合作研究：纳米生物相互作用对多孔介质中纳米颗粒命运和传输的影响

• 批准号: 1704326
• 负责人: John Fortner
• 金额: $ 16万
• 依托单位: Washington University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1704326&HistoricalAwards=false
• 关键词: UNS; Collaborative; Research; Effects; Nano

Despite dramatic increases in the production and use of engineered nanomaterials in industrial and consumer products, very little is known about the fate and transport of nanoparticles following their release into the environment. The overall goal of this project is to better understand the interactions between engineered nanoparticles and microbial communities, and to use this information to improve predictions of nanoparticle accumulation and mobility in soils, groundwater, and water treatment systems. To broaden the educational outreach and practical implications of this work, the project includes research experiences for undergraduate students and the development of interactive, multi-media instructional tools that will be incorporated into educational and training programs run by the Center for Engineering Education and Outreach and Center for Science, Technology, Engineering and Math Diversity. Research conducted over the past ten years has greatly improved our knowledge of nanoparticle aggregation and mobility over a range of environmentally-relevant conditions, and has informed the development of mathematical models capable of describing nanoparticle transport and retention in membranes, filter beds and aquifer materials. At the same time, numerous studies have explored the impacts of nanoparticles on cellular systems, aquatic invertebrates, fish, and microorganisms. The overall goal of this research project is to combine these two lines of research to investigate the role of nano-bio interactions on nanoparticle fate and transport in porous media. The research project is coupling nanoparticle characterization and biotic experiments with dynamic transport studies to quantify the effects of nano-bio interactions on the mobility and fate of representative engineered nanomaterials (iron oxide and magnesium oxide) in aquifer materials and natural soils. Research activities are being structured around three tasks, (1) determination of nanoparticle deposition and release as a function of surface coating aging, biopolymers, and solution composition using a quartz crystal microbalance, (2) assessment of the effects of biopolymers on nanomaterial mobility and retention in abiotic columns, and (3) measurement of nanoparticle transport, deposition, and aging in aerobic and anaerobic bio-active soil columns. Novel aspects of the research include the direct coupling of microbial-particle interactions with transport, assessment of bio-related deposition, direct observation of nanoparticle behavior using flow-through scanning electron microscopy and cryo-transmission electron microscopy techniques. Results obtained from this work are being used to explore the role of microbial communities in the aging nanoparticle surface coatings, and the impacts of filter ripening and site blocking on nanoparticle attachment processes and mobility in the environment. To extend the impact of this work beyond traditional academic boundaries, research outcomes are being incorporated into model-based tutorials, short instructional videos, and illustrative case studies and modeling tools that will be disseminated through collaborations and participation in initiatives with the Center for Science Technology, Engineering and Math Diversity, the Bridge to Engineering Success at Tufts, and the Center for Engineering Education and Outreach at Brown.

尽管工业和消费品中工程纳米材料的生产和使用急剧增加，但人们对纳米粒子释放到环境中后的命运和运输知之甚少。该项目的总体目标是更好地了解工程纳米粒子和微生物群落之间的相互作用，并利用这些信息来改进对土壤、地下水和水处理系统中纳米粒子积累和迁移性的预测。为了扩大这项工作的教育范围和实际影响，该项目包括本科生的研究经验以及交互式多媒体教学工具的开发，这些工具将纳入工程教育和推广中心运营的教育和培训项目中，科学、技术、工程和数学多样性中心。过去十年进行的研究极大地提高了我们对纳米颗粒在一系列环境相关条件下的聚集和流动性的了解，并为能够描述纳米颗粒在膜、滤床和含水层材料中的传输和保留的数学模型的发展提供了信息。与此同时，大量研究探索了纳米颗粒对细胞系统、水生无脊椎动物、鱼类和微生物的影响。该研究项目的总体目标是将这两条研究路线结合起来，研究纳米生物相互作用对多孔介质中纳米颗粒命运和传输的作用。该研究项目将纳米颗粒表征和生物实验与动态运输研究结合起来，以量化纳米生物相互作用对含水层材料和天然土壤中代表性工程纳米材料（氧化铁和氧化镁）的流动性和命运的影响。研究活动围绕三项任务进行：(1) 使用石英晶体微天平确定纳米颗粒沉积和释放与表面涂层老化、生物聚合物和溶液成分的关系，(2) 评估生物聚合物对纳米材料流动性的影响，以及(3)测量纳米颗粒在需氧和厌氧生物活性土壤柱中的运输、沉积和老化。该研究的新颖之处包括微生物-颗粒相互作用与运输的直接耦合、生物相关沉积的评估、使用流通式扫描电子显微镜和低温透射电子显微镜技术直接观察纳米颗粒的行为。这项工作获得的结果被用来探索微生物群落在老化的纳米颗粒表面涂层中的作用，以及过滤器成熟和位点阻塞对纳米颗粒附着过程和环境中移动性的影响。为了将这项工作的影响扩展到传统学术界限之外，研究成果将被纳入基于模型的教程、简短的教学视频以及说明性案例研究和建模工具中，这些内容将通过与科学技术中心的合作和参与计划来传播、工程和数学多样性、塔夫茨大学工程成功之桥以及布朗大学工程教育和外展中心。

项目成果

Effect of rhamnolipid biosurfactant on transport and retention of iron oxide nanoparticles in water-saturated quartz sand

鼠李糖脂生物表面活性剂对水饱和石英砂中氧化铁纳米粒子传输和保留的影响

• DOI: 10.1039/d0en01033b
• 发表时间: 2021-01-28
• 期刊: Environmental science. Nano
• 作者: Shuchi Liao;A. Ghosh;M. Becker;L. Abriola;Natalie L. Cápiro;J. Fortner;K. Pennell
• 通讯作者: K. Pennell

Surface-Engineered Nanomaterials in Water: Understanding Critical Dynamics of Soft Organic Coatings and Relative Aggregation Density

水中的表面工程纳米材料：了解软有机涂层的临界动力学和相对聚集密度

• DOI: 10.1021/acs.est.0c02137
• 发表时间: 2020-11
• 期刊: Environmental Science & Technology
• 影响因子: 11.4
• 作者: Kim, Changwoo;Fortner, John D.
• 通讯作者: Fortner, John D.

Delineating the Relationship between Nanoparticle Attachment Efficiency and Fluid Flow Velocity

描述纳米粒子附着效率与流体流速之间的关系

• DOI: 10.1021/acs.est.0c02669
• 发表时间: 2020-11
• 期刊: Environmental Science & Technology
• 影响因子: 11.4
• 作者: Kim, Changwoo;Pennell, Kurt D.;Fortner, John D.
• 通讯作者: Fortner, John D.

Modeling performance of rhamnolipid-coated engineered magnetite nanoparticles for U( vi ) sorption and separation

鼠李糖脂包被的工程磁铁矿纳米颗粒用于 U( vi ) 吸附和分离的建模性能

• DOI: 10.1039/d0en00416b
• 发表时间: 2020-07
• 期刊: Environmental Science: Nano
• 作者: Sharma, Neha;Ghosh, Anushree;Fortner, John D.;Giammar, Daniel E.
• 通讯作者: Giammar, Daniel E.