Analytical Applications of Surface-Enhanced Hyper-Raman Scattering

表面增强超拉曼散射的分析应用

基本信息

批准号：
1709566
负责人：
Jon Camden
金额：
$ 40万
依托单位：
University of Notre Dame
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
2017
资助国家：
美国
起止时间：
2017-06-01 至 2021-05-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1709566&HistoricalAwards=false
关键词：
Analytical Applications Surface Enhanced Hyper

项目摘要

With support from the Chemical Measurement and Imaging Program in the Division of Chemistry, Professors Camden and Svarovsky of the University of Notre Dame will undertake a study of the analytical applications of the surface-enhanced hyper-Raman scattering (SEHRS) effect and implement a student-driven program to monitor the concentration of uranium in ground water sources. SEHRS is a technique provide unique information about molecules adsorbed on a surface. The success of this work has the potential to impact a wide range of studies, especially the geometry of a molecule adsorbed on a surface differs in complex environments. It can also make a difference in deep-tissue imaging. Furthermore, Professors Camden and Svarovsky and their groups also work on ways to reduce the cost of SEHRS spectrometers, making SEHRS accessible to a wide range of researchers and analytical problems. Students working in these two labs have a great opportunity to learn different skills through collaboration. As a way to engage a new and national K-12 audience in outreach efforts, Professors Camden and Svarovsky also plan to work with the University of Notre Dame's Center for STEM Education together and launch a new Citizen Science project called U-Watch. The program will bring the benefits of surface-based spectroscopy research supported by this grant to a broad audience and could identify potentially dangerous levels of contamination, such as uranium, in ground water drinking sources.In this work, SEHRS is used to provide information that is not available via other techniques. New methods for single-molecule SEHRS are used to probe nanoparticle-adsorbate interactions at the level of single molecules in complex chemical environments. SEHRS nanoparticles also serve as a platform for near-infrared and short-wave-infrared (SWIR) (0.8-2.5 Pm) sensing, imaging, and authentication. The Notre Dame groups also plan to develop the characterization methods needed to pursue the rational design of SWIR tags and apply them to deep-tissue imaging studies. A comparison of SEHRS and surface-enhanced Raman spectroscopy (SERS) shows that SEHRS can be more sensitive than SERS in certain situations. Lastly, they explore the potential for hand-held, field-portable devices capable of recording SEHRS spectra with continuous-wave lasers. Through the supported research, the groups will demonstrate SEHRS as a powerful and practical analytical approach to ultrasensitive detection, imaging, and the elucidation of surface structure and environment.

在化学系化学测量和成像项目的支持下，圣母大学的 Camden 和 Svarovsky 教授将开展表面增强超拉曼散射 (SEHRS) 效应的分析应用研究，并实施一项学生项目监测地下水源中铀浓度的驱动计划。 SEHRS 是一种提供有关表面吸附分子的独特信息的技术。这项工作的成功有可能影响广泛的研究，特别是吸附在表面上的分子的几何形状在复杂环境中会有所不同。它还可以对深层组织成像产生影响。此外，Camden 和 Svarovsky 教授及其团队还致力于降低 SEHRS 光谱仪成本的方法，使 SEHRS 可供广泛的研究人员和分析问题使用。在这两个实验室工作的学生有很好的机会通过合作学习不同的技能。作为吸引新的全国 K-12 受众参与推广工作的一种方式，卡姆登和斯瓦洛夫斯基教授还计划与圣母大学 STEM 教育中心合作，启动一个名为 U-Watch 的新公民科学项目。该计划将把这笔赠款支持的基于表面的光谱学研究的好处带给广大受众，并可以识别地下水饮用水源中潜在危险的污染水平，例如铀。在这项工作中，SEHRS 用于提供以下信息：无法通过其他技术获得。单分子 SEHRS 的新方法用于探测复杂化学环境中单分子水平的纳米颗粒-吸附物相互作用。 SEHRS 纳米颗粒还可用作近红外和短波红外 (SWIR) (0.8-2.5 Pm) 传感、成像和身份验证的平台。圣母大学小组还计划开发合理设计短波红外标签所需的表征方法，并将其应用于深层组织成像研究。 SEHRS 和表面增强拉曼光谱 (SERS) 的比较表明，在某些情况下，SEHRS 比 SERS 更灵敏。最后，他们探索了能够使用连续波激光器记录 SEHRS 光谱的手持式现场便携式设备的潜力。通过支持的研究，这些小组将证明 SEHRS 是一种强大且实用的分析方法，可用于超灵敏检测、成像以及表面结构和环境的阐明。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Non-Condon Effects in the Resonance Hyper-Raman Scattering of Chalcogen-Substituted Rhodamine Derivatives

DOI：
10.1021/acs.jpcc.8b07507
发表时间：
2018-10
期刊：
The Journal of Physical Chemistry C
影响因子：
0
作者：
Jacob E. Olson;Alicia Tripp;Michelle K. Linder;Zhongwei Hu;M. Detty;L. Jensen;J. Camden
通讯作者：
Jacob E. Olson;Alicia Tripp;Michelle K. Linder;Zhongwei Hu;M. Detty;L. Jensen;J. Camden

In Situ Probing of Laser Annealing of Plasmonic Substrates with Surface-Enhanced Raman Spectroscopy.

DOI：
10.1021/acs.jpcc.8b01443
发表时间：
2018-05
期刊：
The journal of physical chemistry. C, Nanomaterials and interfaces
影响因子：
0
作者：
Chaoxiong Ma;Kaiyu Fu;M. J. Trujillo;Xin Gu;Nameera F. Baig;P. Bohn;J. Camden
通讯作者：
Chaoxiong Ma;Kaiyu Fu;M. J. Trujillo;Xin Gu;Nameera F. Baig;P. Bohn;J. Camden

SERS Sensors: Recent Developments and a Generalized Classification Scheme Based on the Signal Origin