Technician Training in Gene Editing

基因编辑技术人员培训

• 批准号: 1700660
• 负责人: John McDowell
• 金额: $ 89.53万
• 依托单位: Delaware Technical & Community College Stanton-Newark Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1700660&HistoricalAwards=false
• 关键词: Technician; Training; Gene; Editing

The rapid expansion of CRISPR/Cas9 gene editing into every subdiscipline of biomedical research requires concomitant training of qualified technicians. The Technician Training in Gene Editing (TTiGE) project addresses this need through a collaboration between instructors at Delaware Technical Community College (DTCC) and scientists at the Gene Editing Institute (GEI). Through this partnership, the latest techniques and applications of gene editing being used in the research settings of GEI will be integrated into student-centered curriculum in several courses in the DTCC Biotechnology program. These activities will then be disseminated nationally to community college instructors through workshops with instruction in gene editing techniques. Training will also be provided in using high impact instruction in the classroom which has been proven to have significant impact on retention in STEM programs. By training instructors, the number of students receiving training in CRISPR gene editing techniques has the potential to support the increase use of gene editing in bioscience companies and research laboratories throughout the nation.The goal of the TTiGE project is to increase the number of biotechnology technicians knowledgeable in CRISPR/Cas9 gene editing and associated skills. A GEI technician will be supported to transfer gene editing technical knowledge and advances to DTCC faculty who will create high impact curriculum to be incorporated into several classes in the Biotechnology program. This program further enhances the Biotechnology program which was strengthened by incorporation of active learning and undergraduate research (Award # 1003649). Two and five-day workshops will be developed to train community college faculty in gene editing techniques in yeast and mammalian cells and the use of student-centered curriculum. Follow-up communication will provide workshop attendees with technical and educational support and disseminate the latest technical advancements in the field. Project evaluation will measure the impact on Delaware Tech students and track incorporation of the materials into courses by workshop attendees. The teacher training in student-centered pedagogy will build teacher confidence to expand these practices into other courses with the goal of increasing retention and graduation rates of bioscience students. The gene editing focus of the TTiGE project insures that technicians are graduating with critical entry-level skills enriched with employability skills.

CRISPR/CAS9基因编辑的快速扩展到生物医学研究的每个子学科都需要对合格技术人员进行伴随培训。基因编辑（TTIGE）项目的技术人员培训通过特拉华州技术社区学院（DTCC）的教练与基因编辑研究所（GEI）的科学家之间的合作解决了这一需求。通过这种合作伙伴关系，在DTCC生物技术计划中的多个课程中，将使用在GEI研究环境中使用的基因编辑的最新技术和应用。然后，这些活动将通过基因编辑技术的教学讲习班将全国范围内传播给社区大学的讲师。还将在课堂上使用高影响力教学的培训，这被证明对STEM计划的保留有重大影响。通过培训讲师，接受CRISPR基因编辑技术培训的学生人数有可能支持在整个国家的生物科学公司和研究实验室中增加基因编辑的使用。TTIGE项目的目的是增加生物技术技术人员在CRISPR/CAS9基因编辑和相关技能中知识渊博的生物技术技术人员的数量。将支持一名GEI技术人员将基因编辑技术知识和进步转移给DTCC教师，DTCC教师将创建高影响力课程，并将其纳入生物技术计划中的几个类别。该计划进一步增强了生物技术计划，该计划通过纳入活跃的学习和本科研究来加强（奖项＃1003649）。将开发两天和五天的研讨会，以培训酵母和哺乳动物细胞中基因编辑技术的社区大学教师以及以学生为中心的课程。后续沟通将为与会人员提供技术和教育支持，并传播该领域的最新技术进步。项目评估将衡量对特拉华科技学生的影响，并跟踪材料将材料纳入研讨会的参与者。以学生为中心的教师的教师培训将建立教师的信心，将这些实践扩展到其他课程中，以提高生物科学学生的保留率和毕业率。 TTIGE项目的基因编辑重点确保技术人员正在以具有就业能力的重要入门级技能毕业。