ARTS: A revisionary monograph of fungi in the genus Fusarium

ARTS：镰刀菌属真菌修订专着

• 批准号: 1655980
• 负责人: David Geiser
• 金额: $ 120万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1655980&HistoricalAwards=false
• 关键词: ARTS; revisionary; monograph; fungi; genus

Fungi in the genus Fusarium cause plant, animal, and human diseases, and produce toxins that contaminate food around the world. Despite their importance and ubiquity, the genus needs a complete taxonomic revision. Only about half of the roughly 300 species we know about even have names, as a result many researchers are not able to get satisfying answers about this group. This project will produce a new monograph of Fusarium that provides a complete description of all currently known species in this genus. Importantly, this monograph will provide a direct electronic link with two key resources: 1) Fusarium specimens in major culture collections that are available for further research and 2) databases of DNA sequence data with a sequence-based classification tool. The electronic portability of the monograph will enable connecting to portals for biological diversity such as Encyclopedia of Life and Wikipedia. This resource will also allow the discovery and recognition of new species of Fusarium, even in well-studied environments such as soils and plants. This project will train two PhD students and a postdoctoral scholar, broaden the training of the PIs, and facilitate collaborations with diverse scientists and students from around the world. This project will utilize new and existing gene sequence data to inform the first full taxonomic treatment of this key genus in over thirty years. The monograph will include introductory chapters that summarize the biological and ecological diversity of the genus. A Fusarium Basics Guide distilled from the monograph will be aimed at the many individuals who use morphology for identification. Individual species descriptions will be arranged based on evolutionary relationships, and will include morphological, ecological and other information. It will also include links to lists of isolates that are available and the data associated with them. Existing barcode gene sequences of the isolates, as well as existing poorly identified Fusarium sequences, will be curated to correct the taxonomy. This curated information will maximize their impact in studies that utilize sequence-based classification. Of particular importance is providing curated datasets that are accessible to bioinformatics platforms used to classify sequences derived from environmental DNA studies.

fusarium属的真菌会引起植物，动物和人类疾病，并产生在世界各地污染食物的毒素。尽管它们的重要性和普遍性，但该属仍需要进行完整的分类修订。我们知道甚至有名字的大约300种中，只有大约一半，因此，许多研究人员无法获得有关该组的满意答案。该项目将制作出新的镰刀菌专着，该专着对该属中当前所有已知物种的完整描述。重要的是，该专着将提供具有两个关键资源的直接电子链接：1）主要培养收集中的镰刀菌样本，可用于进一步研究，以及2）具有基于序列的分类工具的DNA序列数据数据库。该专着的电子可移植性将使生物多样性（例如生命和维基百科百科全书）连接到门户。即使在诸如土壤和植物之类的经过良好研究的环境中，该资源也将允许发现和识别新的镰刀菌种类。该项目将培训两名博士学位学生和一名博士后学者，扩大PIS的培训，并促进与世界各地的不同科学家和学生的合作。该项目将利用新的和现有的基因序列数据为三十年来对这一关键属的第一个完整分类治疗提供信息。该专着将包括总结该属的生物学和生态多样性的介绍章节。从专着提取的镰刀菌基本指南将针对许多使用形态进行识别的人。单个物种描述将根据进化关系进行安排，并包括形态学，生态和其他信息。它还将包括指向可用隔离株列表的链接以及与它们关联的数据。分离株的现有条形码基因序列以及现有的未鉴定的镰刀菌序列将策划以纠正分类法。这些策划的信息将最大程度地利用基于序列分类的研究中的影响。特别重要的是提供策划的数据集，这些数据集可用于用于对环境DNA研究得出的序列进行分类的生物信息学平台。

项目成果

Unambiguous identification of fungi: where do we stand and how accurate and precise is fungal DNA barcoding?

• DOI: 10.1186/s43008-020-00033-z
• 发表时间: 2020-07-10
• 期刊: IMA FUNGUS
• 影响因子: 5.4
• 作者: Luecking, Robert;Aime, M. Catherine;Schoch, Conrad L.
• 通讯作者: Schoch, Conrad L.

Pseudoflowers produced by Fusarium xyrophilum on yellow-eyed grass (Xyris spp.) in Guyana: A novel floral mimicry system?

圭亚那黄眼草（Xyris spp.）上的 Xyrophilum 产生的假花：一种新颖的花拟态系统？

• DOI: 10.1016/j.fgb.2020.103466
• 发表时间: 2020
• 期刊: Fungal Genetics and Biology
• 影响因子: 3
• 作者: Laraba, Imane;McCormick, Susan P.;Vaughan, Martha M.;Proctor, Robert H.;Busman, Mark;Appell, Michael;O'Donnell, Kerry;Felker, Frederick C.;Catherine Aime, M.;Wurdack, Kenneth J.
• 通讯作者: Wurdack, Kenneth J.

Population genetic structure and mycotoxin potential of the wheat crown rot and head blight pathogen Fusarium culmorum in Algeria

• DOI: 10.1016/j.fgb.2017.04.001
• 发表时间: 2017-06-01
• 期刊: FUNGAL GENETICS AND BIOLOGY
• 影响因子: 3
• 作者: Laraba, Imane;Botreghda, Houda;O'Donnell, Kerry
• 通讯作者: O'Donnell, Kerry

Unraveling the ecology and epidemiology of an emerging fungal disease, sea turtle egg fusariosis (STEF)

揭示一种新出现的真菌病——海龟卵镰刀菌病（STEF）的生态学和流行病学

• DOI: 10.1371/journal.ppat.1007682
• 发表时间: 2019
• 期刊: PLOS Pathogens
• 影响因子: 6.7
• 作者: Smyth, Christopher W.;Sarmiento-Ramírez, Jullie M.;Short, Dylan P.;Diéguez-Uribeondo, Javier;O’Donnell, Kerry;Geiser, David M.
• 通讯作者: Geiser, David M.

Marasas et al. 1984 “Toxigenic Fusarium Species: Identity and Mycotoxicology” revisited

• DOI: 10.1080/00275514.2018.1519773
• 发表时间: 2018-11
• 期刊: Mycologia
• 影响因子: 2.8
• 作者: K. O’Donnell;S. McCormick;M. Busman;R. Proctor;T. Ward;Gail Doehring;D. Geiser;J. Alberts;J. Rheeder