Science and Technology Center on Real-Time Functional Imaging (STROBE)

实时功能成像科技中心（STROBE）

• 批准号: 1548924
• 负责人: Margaret Murnane
• 金额: $ 2400万
• 依托单位: University of Colorado at Boulder
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-10-01 至 2026-09-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1548924&HistoricalAwards=false
• 关键词: Science; Technology; Center; Real; Time

Understanding the structure and evolution of matter at the nanometer and atomic scales is central for discovery and innovation in science and technology, accelerating advances in materials science, condensed matter physics, chemistry, biology, engineering, geology, and medicine. This Science and Technology Center (STC) aims to advance and integrate different imaging modalities using electron, X-ray, optical, and nano-probe microscopy to collectively tackle major scientific challenges. It brings together an interdisciplinary team from University of Colorado at Boulder; Universities of California at Berkeley, Los Angeles, and Irvine; Florida International University; and Fort Lewis College, in partnership with national laboratories, US industries, and international collaborators.Education and Diversity: This STC develops, implements, assesses, and disseminates new programs to educate a diverse group of students to be innovative and globally competitive in imaging science and technology. It focuses particularly on two signature efforts: (i) new multidisciplinary graduate certificate and degree programs and (ii) multi-year, cross-institutional undergraduate, master's, and Ph.D. degree programs. The center's education activities are designed to realize the following version of the future: K-12 students will apprehend the exciting opportunities of science and engineering careers. Undergraduate students will appreciate the connections between different areas of science and engineering, as well as the relation between these fields and industry. Ph.D. graduates will acquire expertise with depth and breadth to innovate, lead team research, and create new technologies through entrepreneurship.Knowledge Transfer: This STC aims to manifest through national and international leadership in cutting-edge imaging science, highly-needed diverse graduates trained in multidisciplinary science, and a plethora of hybrid/adaptive imaging modalities and tabletop systems, enabling new science to emerge in the upcoming decades, as well as technology transfer to industry and emerging startups. Faster, higher-resolution and more sensitive imaging techniques will benefit a wide range of scientific disciplines as well as various industrial sectors, which can directly translate technological advances to improving the economy and the standard of living.Technical Description of the Center Research:A major goal of this STC is to address key cross-cutting challenges common to all imaging modalities and tackle science grand challenges across different disciplines. When advances in high-speed direct detectors, advanced algorithms, big-data manipulation methods, new light and electron sources (including tabletop coherent X-ray sources), and spectrally/spatially/temporally structured illumination are integrated, they can fundamentally transform imaging science to enable real-time three-dimensional functional imaging. In addition, by combining electron with optical imaging, or coherent X-ray imaging with ultrafast lasers, or coherent infrared spectroscopies with nano-probe imaging, scientists in this center investigate new hybrid and adaptive imaging modalities that far exceed current capabilities. An expected outcome is creation and integration of a new set of powerful and broadly applicable real-time imaging modalities that can image non-crystalline systems and implement dynamic imaging with a large field of view with chemical and magnetic contrast and with atomic/molecular/nanoscale resolution. Each imaging technique will be brought to reach its fundamental limits and integrated in hybrid/adaptive modalities that surpass the sum of the parts.

了解纳米和原子尺度物质的结构和演化对于科学技术的发现和创新、加速材料科学、凝聚态物理、化学、生物学、工程、地质学和医学的进步至关重要。该科学技术中心 (STC) 旨在利用电子、X 射线、光学和纳米探针显微镜推进和集成不同的成像模式，共同应对重大科学挑战。它汇集了来自科罗拉多大学博尔德分校的跨学科团队；加州大学伯克利分校、洛杉矶分校和欧文分校；佛罗里达国际大学；和路易斯堡学院，与国家实验室、美国工业界和国际合作者合作。教育和多样性：该 STC 开发、实施、评估和传播新项目，以教育多元化的学生群体在成像科学领域具有创新能力和全球竞争力和技术。它特别关注两项标志性工作：(i) 新的多学科研究生证书和学位课程，以及 (ii) 多年、跨机构本科、硕士和博士学位课程。学位课程。该中心的教育活动旨在实现以下版本的未来：K-12 学生将领会科学和工程职业的令人兴奋的机会。本科生将欣赏科学和工程不同领域之间的联系，以及这些领域与行业之间的关系。博士毕业生将获得深度和广度的专业知识，以进行创新、领导团队研究并通过创业创造新技术。知识转移：该 STC 旨在通过尖端成像科学领域的国内和国际领导力来体现，急需接受多学科培训的多元化毕业生科学，以及大量的混合/自适应成像模式和桌面系统，使新科学在未来几十年内出现，以及向工业和新兴初创企业的技术转让。更快、更高分辨率和更灵敏的成像技术将惠及广泛的科学学科以及各个工业部门，可以直接将技术进步转化为改善经济和生活水平。 中心研究的技术描述：主要该 STC 的目标是解决所有成像模式共同的关键跨领域挑战，并应对不同学科的科学重大挑战。当高速直接探测器、先进算法、大数据处理方法、新光源和电子源（包括桌面相干 X 射线源）以及光谱/空间/时间结构化照明的进步集成在一起时，它们可以从根本上改变成像科学以实现实时三维功能成像。此外，通过将电子与光学成像、相干 X 射线成像与超快激光相结合、或相干红外光谱与纳米探针成像相结合，该中心的科学家们研究了远远超出当前能力的新型混合和自适应成像模式。预期成果是创建和集成一套新的强大且广泛适用的实时成像模式，这些模式可以对非晶体系统进行成像，并通过化学和磁对比以及原子/分子/纳米尺度实现大视场动态成像解决。每种成像技术都将达到其基本极限，并集成到超越各部分总和的混合/自适应模式中。