Design and Self-Assembly of Giant Metallo-Supramolecules Based on Density of Coordination Sites (DOCS)

基于配位点密度（DOCS）的巨型金属超分子的设计与自组装

• 批准号: 1506722
• 负责人: Xiaopeng Li
• 金额: $ 43.79万
• 依托单位: Texas State University - San Marcos
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-15 至 2016-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1506722&HistoricalAwards=false
• 关键词: Design; Self; Assembly; Giant; Metallo

In this project funded by the Macromolecular, Supramolecular, and Nanochemistry Program of the Division of Chemistry, Xiaopeng Li of Texas State University and his coworkers will design and synthesize ligands with well-defined geometry and multiple coordination sites and characterize the 2D and 3D supramolecular structures resuling therefrom. A wide variety of biological molecules (such as DNAs and proteins) have very complex structures and 3-dimensional (3D) architectures that are important for their biological functions. Inspired by nature, Prof. Li conducts research to develop self-assembly strategies to creating complex chemical structures with unique properties. Of particular interest is the preparation of metallo-gels with self-healing properties that may be useful in batteries. This project is expected to provide an excellent platform for interdisciplinary research training of postdoctoral associates, graduate students, and undergraduate students, especially underrepresented minorities from the South Central Texas region.The targeted metallosupramolecular structures are envisioned to result from the coordination of metal ions (e.g., Zn(II), Fe(II) and Pd(II)) by the designed multitopic ligands. The research team will prepare metallo-gels and explore their potential applications as self-healing materials and binder materials of batteries. The level of complexity is often attained by self-assembly of structurally simple subunits (or building blocks) which have specific functionalities and geometries to direct their assembly into sophisticated structures of precisely controlled size, shape and properties.The Li research group aims to gain insights into the fundamental chemistry principles that control supramolecular self-assemblies and to prepare novel materials with unique properties.

在这个由化学系高分子、超分子和纳米化学项目资助的项目中，德克萨斯州立大学的李晓鹏及其同事将设计和合成具有明确几何形状和多个配位位点的配体，并表征2D和3D超分子结构由此产生的。 多种生物分子（例如 DNA 和蛋白质）具有非常复杂的结构和 3 维 (3D) 架构，这对其生物功能非常重要。 受到大自然的启发，李教授进行了研究，开发自组装策略，以创建具有独特性能的复杂化学结构。 特别令人感兴趣的是具有自愈特性的金属凝胶的制备，该金属凝胶可用于电池。 该项目预计将为博士后、研究生和本科生，特别是来自德克萨斯州中南部地区代表性不足的少数族裔的跨学科研究培训提供一个优秀的平台。目标金属超分子结构预计是由金属离子（例如， 、Zn(II)、Fe(II) 和 Pd(II)) 通过设计的多位配体。研究团队将制备金属凝胶并探索其作为自修复材料和电池粘合剂材料的潜在应用。 复杂程度通常是通过结构简单的子单元（或构建块）的自组装来实现的，这些子单元具有特定的功能和几何形状，可将其组装成尺寸、形状和属性精确控制的复杂结构。李研究小组的目标是获得见解研究控制超分子自组装和制备具有独特性能的新型材料的基本化学原理。