The role of memory strength for processes of sleep-associated memory consolidation

记忆强度在睡眠相关记忆巩固过程中的作用

• 批准号: 214564547
• 负责人: Professor Dr. Karl-Heinz Bäuml
• 金额: --
• 依托单位: Lehrstuhl für Psychologie IV (Entwicklungs- und Kognitionspsychologie)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2012
• 资助国家: 德国
• 起止时间: 2011-12-31 至 2015-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/214564547?language=en
• 关键词: role; memory; strength; processes; sleep

While recent findings demonstrate that processes of sleep-associated memory consolidation can stabilize memories, it is unclear whether such consolidation varies with one of the most basic features of memory representations, i.e., memories’ initial strength. The aim of this project is to fill this empirical gap by examining the role of memory strength for memory consolidation, behaviorally and neuroscientifically. Across 13 experiments, memory strength will be manipulated using intentional and incidental encoding procedures; intentional manipulations of strength will be examined in the paired associate task and the list learning task and will be implemented by study-induced and retrieval-induced strengthening; incidental manipulations of strength will be investigated in the list learning task by using different orienting tasks. Behaviorally, effects of memory consolidation will be measured via investigations of time-dependent forgetting and memories’ interference susceptibility. Neuronally, electroencephalography (EEG) will be used to study how manipulations of encoding strength change the neural correlates of initial memory formation and change retrieval processing right after encoding as well as following 12 hours of sleep or wakefulness. In addition, sleep EEG will be employed to examine sleep mechanisms believed to be directly involved in the reactivation and restructuring of newly formed memories. The results will provide a first overall picture on the role of memory strength for sleep-associated memory consolidation.

虽然与睡眠相关的记忆巩固过程的最新发现可以稳定记忆，而记忆的最基本知识之一，即记忆的初始强度。记忆在行为上和神经上的力量。干扰性l与trieval的处理右边的编码以及觉醒的次数相关。合并。

项目成果

Oscillatory Theta Activity during Memory Formation and Its Impact on Overnight Consolidation: A Missing Link?

• DOI: 10.1162/jocn_a_00804
• 发表时间: 2015-08-01
• 期刊: JOURNAL OF COGNITIVE NEUROSCIENCE
• 影响因子: 3.2
• 作者: Heib, Dominik P. J.;Hoedlmoser, Kerstin;Schabus, Manuel
• 通讯作者: Schabus, Manuel