REU Site: Research Experiences for Underrepresented Minority Undergraduates in Basica and Genetic Research at Louisiana State University Health Sciences Center (LSUHSC)

REU 网站：路易斯安那州立大学健康科学中心 (LSUHSC) 代表性不足的少数族裔本科生在基础和遗传学研究方面的研究经验

• 批准号: 1359140
• 负责人: Fern Tsien
• 金额: $ 29.56万
• 依托单位: Louisiana State University Health Sciences Center
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-15 至 2017-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1359140&HistoricalAwards=false
• 关键词: REU; Site; Research; Experiences; Underrepresented

This REU Site award to the Louisiana State University Health Sciences Center in New Orleans, LA will support the training of 10 students for 10 weeks during the summers of 2014-16. Training will focus on research fields including genetics, microbiology, biochemistry, neurosciences, physiology, and pharmacology. Sample projects include: the study of proteins involved in DNA repair, cell cycle, and signal transduction; the regulation of transcription factors through phosphorylation; and the analysis of the platelet-activating factor (PAF) signaling in interneuronal rearrangements. The program will provide students with one-on-one mentoring on hypothesis development, experimental design, research methods, and scientific presentation skills. Students will learn how research is conducted and many will present the results of their work at scientific conferences. Interactive workshops will include topics such as resume writing for graduate school applications, responsible conduct in research, and discussions of career pathways with faculty members from the LSUHSC Basic Sciences Departments and Centers.Students will be selected for participation based on academic record, research interest, and plans for a career in scientific research. Students attending Historically Black Colleges and Universities and from schools with limited research opportunities are encouraged to apply. The program is targeting undergraduates from diverse social and educational backgrounds, especially from the New Orleans area. REU program alumni will be recruited to volunteer at partnering K-12 New Orleans schools during the academic year where they will explain biology and genetics to science classes and serve as role models to younger generations of potential scientists. Assessment of the program is by qualitative and quantitative participant surveys, mentor evaluations, and by the BIO/REU common assessment tool. Students are required to be tracked after the program and must respond to an automatic email sent via the NSF reporting system. More information is available by visiting http://www.medschool.lsuhsc.edu/genetics/reu.aspx or by contacting the PI (Dr. Fern Tsien at [e-mail]).

REU 授予位于路易斯安那州新奥尔良的路易斯安那州立大学健康科学中心的场地奖将支持 10 名学生在 2014-16 年夏季进行为期 10 周的培训。培训将集中于遗传学、微生物学、生物化学、神经科学、生理学和药理学等研究领域。示例项目包括：研究参与 DNA 修复、细胞周期和信号转导的蛋白质；通过磷酸化调节转录因子；以及神经元间重排中血小板激活因子（PAF）信号传导的分析。该项目将为学生提供关于假设发展、实验设计、研究方法和科学表达技巧的一对一指导。 学生将了解如何进行研究，许多人将在科学会议上展示他们的工作成果。 互动研讨会将包括研究生院申请简历写作、负责任的研究行为以及与 LSUHSC 基础科学系和中心的教员讨论职业道路等主题。将根据学术记录、研究兴趣、并计划从事科学研究。 鼓励就读历史悠久的黑人学院和大学以及研究机会有限的学校的学生申请。 该计划针对来自不同社会和教育背景的本科生，尤其是来自新奥尔良地区的本科生。 REU 项目校友将在学年期间被招募到新奥尔良 K-12 合作学校担任志愿者，在那里他们将向科学课解释生物学和遗传学，并为年轻一代潜在科学家充当榜样。该计划的评估是通过定性和定量的参与者调查、导师评估以及 BIO/REU 通用评估工具进行的。学生需要在课程结束后进行跟踪，并且必须回复通过 NSF 报告系统发送的自动电子邮件。如需了解更多信息，请访问 http://www.medschool.lsuhsc.edu/genics/reu.aspx 或联系 PI（Fern Tsien 博士，[e-mail]）。

项目成果

Mini-review on "A novel one-step purification of mouse factor IX"

“一种新颖的一步纯化小鼠因子 IX”的小评论

• DOI: 10.29245/2572-9411/2016/2.1031
• 发表时间: 2016
• 期刊: Journal of Rare Diseases Research & Treatment
• 作者: Majumder, Rinku

High fat diet consumption differentially affects adipose tissue inflammation and adipocyte size in obesity-prone and obesity-resistant rats.

• DOI: 10.1038/ijo.2017.280
• 发表时间: 2018-03
• 期刊: International journal of obesity (2005)
• 作者: Poret JM;Souza-Smith F;Marcell SJ;Gaudet DA;Tzeng TH;Braymer HD;Harrison-Bernard LM;Primeaux SD
• 通讯作者: Primeaux SD

Disruption of the Putative Ribosome-Binding Motif of a Scaffold Protein Impairs Cytochrome c Oxidase Subunit Expression in Leishmania major

支架蛋白假定核糖体结合基序的破坏会损害大型利什曼原虫细胞色素 c 氧化酶亚基的表达

• DOI: 10.1128/msphere.00644-18
• 发表时间: 2019
• 期刊: mSphere
• 影响因子: 4.8
• 作者: Cardenas, Daviel;Sylvester, Charity;Cao, Bo;Nation, Catherine S.;Pizarro, Juan C.;Lu, Hua;Guidry, Jessie;Wojcik, Edward J.;Kelly, Ben L.
• 通讯作者: Kelly, Ben L.

Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes.

• DOI: 10.1172/jci.insight.137230
• 发表时间: 2020-07
• 期刊: JCI insight
• 影响因子: 8
• 作者: Cristiano P. Vieira;Seth D Fortmann;Masroor Hossain;A. L. Longhini;Sandra S. Hammer;Bright Asare-Bediako;D. Crossman;M. S. Sielski;Yvonne Adu-Agyeiwaah;Mariana Dupont;J. Floyd;S. Li Calzi;Todd A. Lydic;R. Welner;G. Blanchard;J. Busik;M. Grant

Chronic binge alcohol and ovariectomy dysregulate omental adipose tissue metaboproteome in simian immunodeficiency virus-infected female macaques

慢性酗酒和卵巢切除使感染猿猴免疫缺陷病毒的雌性猕猴的网膜脂肪组织代谢蛋白质组失调

• DOI: 10.1152/physiolgenomics.00001.2021
• 发表时间: 2021
• 期刊: Physiological Genomics
• 影响因子: 4.6
• 作者: Poret, Jonquil M.;Guidry, Jessie J.;Simon, Liz;Molina, Patricia E.
• 通讯作者: Molina, Patricia E.