SBIR Phase I: Engineered Sensors for the Pulmonary Forced Oscillation Technique

SBIR 第一阶段：用于肺强迫振荡技术的工程传感器

• 批准号: 1248714
• 负责人: Charles Forbes
• 金额: $ 14.98万
• 依托单位: Feather Sensors, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-01-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1248714&HistoricalAwards=false
• 关键词: SBIR; Phase; Engineered; Sensors; Pulmonary; SBIR; Phase; Engineered; Sensors; Pulmonary

This Small Business Innovation Research Phase I project will advance the development of a new pulmonary testing instrument. The innovative device utilizes a strain gauge to measure pulmonary airflow, an indicator critical in monitoring the health of asthma and chronic obstructive pulmonary disease (COPD) patients. The research challenge is to develop and demonstrate the feasibility of a customized strain gauge for this device. This will involve fabricating and testing thin film sensors and comparing their efficacy to the commercial sensor now used. The customized sensors will be developed in a university-based clean room and tested against the commercial sensors by comparing signal to noise measurements. Research efforts will aim at improving signal to noise and minimizing non-linear responses seen in the commercial sensor. For this proposal, the specific application of the new sensor will be in a device that will measure pulmonary airflow resistance using the Forced Oscillation Technique (FOT). The broader impact/commercial potential of this project will be to market an instrument that has significant advantages over those currently in use to measure lung airflow of pulmonary disease patients. An estimated 36.4 million Americans suffer from asthma or chronic obstructive pulmonary disease (COPD). Successful development of the proposed assistive technology will offer a low-cost, easily cleaned, readily mobile testing device that is adaptable to home use. The specific application proposed for this device, forced oscillation technique (FOT), has a significant advantage over standard spirometry, as it does not depend upon deliberate cooperation of the patient to perform required respiratory maneuvers. It is therefore useful for comatose patients, infants and children, mentally and physically impaired individuals, and even animals. FOT devices are new developments; they are being used primarily in research settings. The device proposed here will be extremely competitive in the marketplace, primarily due to its low cost, but also to its simple design and ease of use. Software developed for his device will make the wireless transfer of data from the patient?s home to the physician?s office effortless.

这个小型企业创新研究阶段I项目将推动开发新的肺部测试工具。 创新设备利用应变量表来测量肺气流，这对于监测哮喘和慢性阻塞性肺疾病（COPD）患者的健康至关重要。 研究挑战是开发和证明该设备定制的应变仪的可行性。 这将涉及制造和测试薄膜传感器，并将其功效与现在使用的商业传感器进行比较。 定制的传感器将在大学的清洁室中开发，并通过将信号与噪声测量值进行比较，对商业传感器进行了测试。 研究工作将旨在提高信号对噪声，并最大程度地减少商业传感器中看到的非线性响应。 对于此提案，新传感器的特定应用将是在使用强制振荡技术（FOT）测量肺气流阻力的设备中。 该项目的更广泛的影响/商业潜力将是销售一种工具，该工具比目前用来测量肺部疾病患者肺气流动的仪器具有显着优势。 估计有3640万美国人患有哮喘或慢性阻塞性肺疾病（COPD）。 拟议的辅助技术的成功开发将提供适合家庭使用的低成本，易于清洁，易于移动的测试设备。 该设备提出的特定应用是强制振荡技术（FOT），比标准肺活量测定法具有显着优势，因为它不取决于患者故意合作执行所需的呼吸道操作。 因此，它对昏迷的患者，婴儿和儿童，精神和身体受损的个体甚至动物都有用。 FOT设备是新的发展；它们主要用于研究环境。 此处提出的设备在市场上将非常有竞争力，这主要是由于其低成本，也是由于其简单的设计和易用性。 为他的设备开发的软件将使数据从患者的家中无线传输到医生的办公室。