SBIR Phase I: Development of a Commercial Culture of Dehalococcoides for Anaerobic Treatment of PCB's

SBIR 第一阶段：开发用于 PCB 厌氧处理的 Dehalococcoides 商业培养物

• 批准号: 1113457
• 负责人: Margaret Findlay
• 金额: $ 15万
• 依托单位: Bioremediation Consulting Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1113457&HistoricalAwards=false
• 关键词: SBIR; Phase; Development; Commercial; Culture

This Small BusinessI nnovationR esearch( SBIR) Phase1 project addressesth e developmento f abacterial culture to degrade PCBs (polychlorinated biphenyls) in contaminated soils andsediments. PCBs are persistent, toxic contaminants which accumulate in the fatty tissues ofanimals,c ontaminatingf ish and humans.P CB-degradingb acteriah ave beend ifficult to produce.In2009, a readily-grownb acterials peciesw as shownb y BioremediationC onsultingI nc (BCI) todegrade the most harmful and carcinogenic type of PCBs. This finding allows the developmentof an anaerobic PCB-degrading culture for cost-etfective inoculation into PCB-contaminatedsediments. The proposed research will document the ability of BCI's culture to extensivelydechlorinate three types of commercial PCB mixtures, and will develop methods of rapidculturing.The broader/commerciailm pactso f this researcha ret he developmento f a bacteriai noculantt hatwill degrade PCBs in soil and sediment. PCBs are toxic chemicals used historically as heatresistantfluids in many industrial applications, including transformers in the electric utilityindustry. Several hundred million pounds were manufactured and disposed, resulting incontamination of soils and river sediments. The recent finding at BCI, that a strain ofdechlorinating bacteria is capable of dechlorinating PCBs. provides an opportunity for BCI todevelop a commercial culture for inoculating contaminated sites with PCB-degrading bacteria.The marketing of this product will be complementedb y our already-successfusl aleso f otherdechlorinating cultures used in treatment of contamination by diverse chlorinated compounds.Major stakeholdersin the utility industries,a nd remediationc ontractors,h ave expressedin terestin partnering with BCI and/or obtaining culture.

这种小型企业nnovationr esearch（SBIR）阶段1项目地址为含量较高的含PCB（多氯联苯）在受污染的土壤和代码方面降低。 PCBs are persistent, toxic contaminants which accumulate in the fatty tissues ofanimals,c ontaminatingf ish and humans.P CB-degradingb acteriah ave beend ifficult to produce.In2009, a readily-grownb acterials peciesw as shownb y BioremediationC onsultingI nc (BCI) todegrade the most harmful and carcinogenic type PCB的。这一发现允许开发一种厌氧PCB降解培养物，以对PCB污染的种类进行成本感染接种。拟议的研究将记录BCI培养物广泛氯化三种类型的商业PCB混合物的能力，并将开发快速培养的方法。这项研究更广泛/更广泛/商业的方法。在许多工业应用中，PCB是历史上用作HeatresistantFluids的有毒化学物质，包括电力工具的变压器。制造和处置了数亿磅，导致土壤和河流沉积物的灭火。最近在BCI的发现是，氯化细菌的菌株能够脱氯PCB。 provides an opportunity for BCI todevelop a commercial culture for inoculating contaminated sites with PCB-degrading bacteria.The marketing of this product will be complementedb y our already-successfusl aleso f otherdechlorinating cultures used in treatment of contamination by diverse chlorinated compounds.Major stakeholdersin the utility industries,a nd remediationc ontractors,h ave expressedin Terestin与BCI和/或获得文化合作。