EMSW21: RTG: Mathematical and Computational Biofluids

EMSW21：RTG：数学和计算生物流体

• 批准号: 1043626
• 负责人: Lisa Fauci
• 金额: $ 140.21万
• 依托单位: Tulane University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1043626&HistoricalAwards=false
• 关键词: EMSW21; RTG; Mathematical; Computational; Biofluids

Fluid dynamics has historically been a driving force in applied mathematics and scientific computing.In biological settings, a level of complexity is added to traditional fluid dynamics sincetypically biological flows are unsteady, involve active and elastic interfaces, fluid-structure interactionsand transport of chemical signals. This Research and Training project, led by faculty in theDepartments of Mathematics and Biomedical Engineering at Tulane University, recognizes the needfor students trained at the interface of mathematics and the biomedical sciences. Three graduatestudents, six undergraduate students and two postdoctoral fellows will be supported each year. Abroad spectrum of research projects will be emphasized that span mathematical analysis, developmentand analysis of numerical methods for partial differential equations, modeling of complexbiological systems, three-dimensional simulations on high-performance computers, and a two-waycoordination of modeling with experiments. Training activities will include a curriculum with corecourses from both the Department of Mathematics and the Department of Biomedical Engineering,regular group meetings, a monthly Biofluids All-Hands meeting, a wet-lab and internship programfor graduate students and postdocs, professional development seminars, an annual Carnival FocusDays (CFD) workshop and high-performance computing training activities. Moreover, undergraduatestudents will be fully-integrated into research teams through academic year involvement andintensive summer research.Mathematics has had a huge impact on the engineering, biological and physical sciences through its developmentof theoretical analyses and numerical methods. Biological fluid dynamics, in additionto its direct applications in physiology and oceanography, provides a rich educational and trainingplatform for students in the mathematical sciences. Undergraduates, graduate students and postdoctoralstudents will work in teams, with representation from both Mathematics and BiomedicalEngineering, and with an emphasis on the interplay between theory, computation and experiment.Research projects will be motivated by applications, including microorganism motility, pulmonarymechanics, biosensors and cellular biomechanics. All graduate and postdoctoral students will participatein an internship, either at Tulane University or at a partner institution, where they canwork side-by-side with experimentalists, develop a comprehensive understanding of various aspectsof the research project, and participate in the life of a working fluids lab. The co-PIs, all co-foundersof Tulane's Center for Computational Science, have demonstrated commitment to this model oftraining. They are, themselves, diverse, and have been actively involved in increasing the numberof US women and minorities in scientific research. This training program will attract diverseAmerican nationals into the mathematical sciences.

从历史上看，流体动力学一直是应用数学和科学计算的推动力。在生物学环境中，传统的流体动力学含有句号生物流的传统流体动力学不稳定，涉及活性和弹性界面，流体结构的交互和化学信号的运输。该研究与培训项目由杜兰大学数学和生物医学工程学院的教师领导，认识到在数学和生物医学科学界面培训的学生的需求。每年将支持三名毕业生，六名本科生和两个博士后研究员。将强调，国外研究项目的范围将跨越数学分析，部分微分方程的数值方法的开发和分析，复杂生物学系统的建模，高性能计算机上的三维模拟以及实验进行建模的双向道路协调。培训活动将包括与数学系和生物医学工程部，常规小组会议的Corecourss的课程，每月的Biofluids All Beards会议，湿与LAB和实习计划的研究生和研究生，专业发展研讨会，专业发展研讨会，专业发展研讨会，年度嘉年华焦点（CFD）研讨会和高性能计算培训活动。此外，通过学年参与和夏季研究的研究团队将全面融入研究团队，并通过其理论分析和数值方法的开发对工程，生物学和物理科学产生了巨大影响。生物流体动力学除了其在生理和海洋学中的直接应用外，还为数学科学的学生提供了丰富的教育和培训平台。本科生，研究生和博士后学生将以数学和生物培养学发达的代表来工作，并强调理论，计算和实验之间的相互作用。研究将由应用程序激励，包括应用程序，包括微生物，式式机电，生物传感器，生物传感器，生物传感器和细胞动力，派纸条，生物传感器和细胞。生物力学。所有研究生和博士后学生都将在杜兰大学或合作伙伴机构中参加实习，在那里他们可以与实验者并肩作战，对研究项目的各个方面进行全面的了解，并参与工作的生活。流体实验室。杜兰（Tulane）计算科学中心的所有共同创始人的共同创始人都表现出对这种训练模型的承诺。他们本身是多种多样的，并且一直积极参与增加美国妇女和少数群体的科学研究数量。该培训计划将吸引多元化国民进入数学科学。