EFRI-SEED: Energy Minimization via Multi-Scaler Architectures From Cell Contractility to Sensing Materials to Adaptive Building Skins

EFRI-SEED：通过多尺度架构实现能量最小化，从细胞收缩性到传感材料再到自适应建筑表皮

• 批准号: 1038215
• 负责人: Shu Yang
• 金额: $ 200万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1038215&HistoricalAwards=false
• 关键词: EFRI; SEED; Energy; Minimization; via

The objective of this EFRI-SEED project is to explore materiality from nano- to macroscales based upon understanding of nonlinear, dynamic human cell behaviors on geometrically-defined substrates. The insights as to how cells can modify their immediate extracellular matrix (ECM) microenvironment with minimal energy and maximal effect will lead to the biomimetic design and engineering of highly aesthetic, passive materials, and sensors and imagers that will be integrated into responsive building skins at the architectural scale. The PIs will (1) use architectural and computational algorithms to guide the design and fabrication of soft substrates with generic 1-D to 3-D geometrical patterns; (2) quantitatively measure and visualize in real-time how human pulmonary artery vascular smooth muscle cells, that interact to contract or relax these substrates to modify substrate geometry; (3) redeploy architectural and algorithmic tools, and model and simulate pattern and material manipulation resulting from nonlinear cellular behaviors so as to transfer this fine-scale design ecology to the macro-scale design of adaptive building skins; (4) apply the understanding to optimal design of materials and geometries that are responsive to environmental factors (e.g. heat, humidity and light); (5) design biomimetic sensors and control systems using CMOS and nanotechnology, and (6) transform the concept from modeling, materials manipulation, and device integration at the nano- and microscales to the design of responsive, yet passive building skins at the architectural and human scale. This project represents a unique avant garde model for sustainable design via the fusion of the architectural design studio with laboratory-based scientific research. In turn, this will benefit a diverse range of science and technologies, including the construction of energy efficient and aesthetic building skins and materials.The project will create a significant opportunity to excite the general public, thereby provoking and engaging their interest in Science, Technology, Engineering, and Mathematics (STEM). This work will offer an effective tool to recruit and train students at all levels in a highly-integrated research and educational environment. The research results will be disseminated through: (1) (bi)weekly chalk talks and faculty retreats at Penn, annual workshops at the Mid-Atlantic region, and national conferences and workshops; (2) The website of LabStudio for new discoveries in cell science, visualization techniques, materials, fabrication, and computational modeling frameworks developed from this project; (3) Advertising the technology through the Lab-to-Market Forum and LabStudio to attract industrial interest, and (4) Installation of architectural models resulted from the research at international exhibitions. The research contains novel and synergistic activities, including: (1) the study of cellular nano- and micro-mechanics in Pathology & Laboratory Medicine (School of Medicine, SOM); (2) materials fabrication and characterization in Materials Science and Engineering (MSE; School of Applied Science & Engineering, SEAS); (3) architectural design, computational modeling, simulation and digital fabrication in design and research labs in Architecture (School of Design, SOD) and Electrical & Systems Engineering (ESE; SEAS) respectively, and (4) device fabrication and integration in labs in ESE.The FY 2010 EFRI-SEED Topic that supports this project was sponsored by the US National Science Foundation (NSF) Directorates for Engineering (ENG), Mathematical and Physical Sciences (MPS) and Social, Behavioral and Economic Sciences (SBE), and Computer & Information Science and Engineering in collaboration with the US Department of Energy (DOE) and the US Environmental Protection Agency (EPA).

这个Efri-seed项目的目的是基于对几何定义的底物的非线性，动态人类细胞行为的理解，探索从纳米 - 宏观到宏观的重要性。关于细胞如何以最小的能量和最大效果修饰细胞如何修改其即时细胞外基质（ECM）微环境的见解将导致高度美观的被动，被动材料的仿生设计和工程，以及将整合到响应式响应式响应式响应式响应式的响应层。建筑规模。 PIS（1）使用架构和计算算法指导具有通用1-D至3-D几何图案的软底物的设计和制造； （2）实时测量和可视化的人类肺动脉血管平滑肌细胞，它们相互作用以收缩或放松这些底物以修饰底物几何形状； （3）重新部署建筑和算法工具，并模型并模拟由非线性细胞行为产生的模式和材料操纵，以便将这种高规模的设计生态学转移到适应性建筑皮肤的宏观设计中； （4）将理解应用于对环境因素响应的材料和几何形状的最佳设计（例如热，湿度和光）； （5）使用CMOS和纳米技术设计仿生传感器和控制系统，（6）将概念从纳米和显微镜的建模，材料操纵和设备集成转变为在体系结构和建筑和被动建筑物的设计的设计人量表。该项目代表了一个独特的前卫Garde模型，用于通过建筑设计工作室与基于实验室的科学研究的融合来实现可持续设计。反过来，这将使各种各样的科学和技术受益，包括建造节能和美学建筑皮肤和材料。该项目将为普通公众兴奋，从而引起他们对科学，技术的兴趣，从而创造一个重要的机会，工程和数学（STEM）。这项工作将为高度综合的研究和教育环境中的各个级别招募和培训学生提供有效的工具。研究结果将通过：（1）（BI）每周在宾夕法尼亚州的粉笔谈判和教职员工，大西洋地区的年度研讨会以及国家会议和研讨会； （2）LabStudio的网站，用于细胞科学，可视化技术，材料，制造和计算建模框架的新发现； （3）通过实验室到市场论坛和LabStudio广告技术，以吸引工业兴趣，（4）安装建筑模型是由国际展览的研究产生的。该研究包含新颖和协同的活动，包括：（1）病理与实验室医学中的细胞纳米和微力学研究（SOM医学院）； （2）材料科学与工程中的材料制造和特征（MSE；应用科学与工程学院，海洋）； （3）在建筑和研究实验室中的建筑设计，计算建模，模拟和数字制造（设计和研究实验室（设计，SOD学院）和电气与系统工程（ESE; SEAS），以及（4）在实验室中的设备制造和集成ESE。支持该项目的2010财年EFRI-SEED主题是由美国国家科学基金会（NSF）工程（ENG），数学和物理科学（MPS）以及社会，行为和经济科学（SBE）以及计算机与信息科学与工程与美国能源部（DOE）和美国环境保护署（EPA）合作。