Novel Platinum and Palladium Reactions Relevant to Hydrocarbon Functionalization

与碳氢化合物官能化相关的新型铂和钯反应

• 批准号: 1012045
• 负责人: Karen Goldberg
• 金额: $ 48.48万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1012045&HistoricalAwards=false
• 关键词: Novel; Platinum; Palladium; Reactions; Relevant

In this project funded by the Chemical Catalysis Program of the Chemistry Division, Professor Karen I. Goldberg of the University of Washington will develop detailed mechanistic understanding of fundamental organometallic reactions that can selectively cleave carbon-hydrogen bonds, can activate molecular oxygen to enable its use as a selective oxidant, and can selectively produce functionalized organic products through the formation of new carbon-carbon and carbon-oxygen bonds. These reactions are vital to study and understand because they can be applied to the manufacturing of chemicals and materials that are essential to our society - from plastics and building supplies, to new agricultural products and pharmaceuticals. Many of these chemicals are produced on huge scales. But the current processes are complex, consume large amounts of energy and/or produce significant waste. Professor Goldberg's efforts may enable chemists to conduct the reactions more quickly and selectively using less energy, using less dangerous reagents, and producing fewer by-products. The broader impacts involve outreach to high school students, teachers, and the general public as well as training of undergraduate and graduate student researchers.This work will enhance our fundamental understanding about catalytic processes. There is a substantial need for more efficient ways of making bulk chemicals from petroleum-based products. In addition, being able to activate and selectively transform C-H bonds in alkanes could significantly impact our dependence on oil by providing new routes to efficiently transport and utilize natural gas reserves.

在由化学部门的化学催化计划资助的该项目中，华盛顿大学的Karen I. Goldberg教授将对基本有机反应的详细机械理解，可以选择性地裂解碳 - 氢键，可以激活分子氧气，使其能够通过选择性地构建了型号的有机化产品，可以将其用作型号的型号，并且可以选择性地形成有机化的型号，并且可以选择有机化的有机化型有机化的型号，债券。这些反应对于研究和理解至关重要，因为它们可以应用于对我们社会至关重要的化学物质和材料的制造 - 从塑料和建筑用品到新的农产品和药品。这些化学物质中的许多是在巨大的尺度上生产的。但是当前的过程很复杂，消耗了大量能量和/或产生大量的废物。戈德堡教授的努力可能使化学家能够使用较少危险的试剂更快，选择性地进行反应，并产生较少的副产品。更广泛的影响涉及向高中生，老师和公众以及对本科和研究生研究人员的培训的宣传。这项工作将增强我们对催化过程的基本理解。从基于石油的产品中制造批量化学物质的更有效方法非常需要。 此外，通过提供有效运输和利用天然气储量的新途径，能够激活和选择性地转化烷烃中的C-H键可以显着影响我们对石油的依赖。