CAREER: Self-Assembly in Two and Three Dimensions: from Crystal to Surface Design and Back

职业：二维和三维自组装：从晶体到表面设计再到背面

• 批准号: 0846426
• 负责人: Angelo Cacciuto
• 金额: $ 58.5万
• 依托单位: Columbia University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0846426&HistoricalAwards=false
• 关键词: CAREER; Self; Assembly; Two; Three

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). TECHNICAL SUMMARYThis CAREER proposal supports an integrated research and education program that centers on solving problems involving colloidal particle self-assembly using theoretical and computational methods. Unlike most of the work done so far in the field that focuses on how order arises from given local interparticle interactions, this research will study the inverse problem of finding what local interactions are required for the building blocks to self-assemble into a given structure. Using this approach, new strategies will be developed to find particle interactions that are capable of generating specific crystal structures through self-assembly. The role of elastic and amphiphatic surfaces in mediating particle self-assembly and the role of particle aggregation in determining the mechanical and elastic properties of soft interfaces will also be studied. The ability to design particle interactions in a systematic fashion to target desired crystals, and the prospect of manipulating the mechanical properties of microscopic elastic sheets, will be results of great practical importance. The results of this research will help open the way to rational design of structures with novel optical, mechanical and functional properties. The educational aspects of this CAREER award are multifaceted. One major goal is to increase participation of underrepresented groups in the sciences and specifically in chemistry by improving K-12 curriculum activities in nearby Harlem high schools. The PI also plans to develop multi-platform interactive educational software, in the particular form of video games, that will be made freely available to middle and high schools nation wide. This approach is based on the premise that active learning and interactivity will be the key to motivate and inspire the next generation of scientists. This outreach program builds on the framework of the Center for Technology, Innovation, and Community Engagement at Columbia University, and complements the ongoing efforts of the Chemistry Department and the University to reach the Harlem community.NONTECHNICAL SUMMARYThis CAREER award supports a combined research and education program to develop theoretical and computational methods that can predict how molecular building blocks will self-assemble into three-dimensional materials structures. This approach could apply to many materials systems, some representative examples include: aggregation of proteins into functional biomachines on the scale of large molecules, formation of protein coats of viruses, packing of large molecules to form biological membranes, and assembly of nanometer scale particles to make photonic crystals, crystals engineered for specific optical properties, such as transmitting particular colors of light and blocking others. The major research objectives include the development of numerical tools to examine how particles need to interact with each other in order to self-assemble into a desired complex crystal structure, the study of how elastic surfaces or membranes can assist particle self-assembly, and the study of how particle clustering on soft interfaces can be used to determine the mechanical and elastic properties of materials used as templates. The results of this research could help open the way to rational design of structures with novel optical, mechanical and functional properties. This program will build on the strong commitment of Columbia University to the field of nanotechnology. The educational aspects of this CAREER award are multifaceted. One major goal is to increase participation of underrepresented groups in the sciences and specifically in chemistry by improving K-12 curriculum activities in nearby Harlem high schools. The PI also plans to develop multi-platform interactive educational software, in the particular form of video games, that will be made freely available to middle and high schools nation wide. This approach is based on the premise that active learning and interactivity will be the key to motivate and inspire the next generation of scientists. This outreach program builds on the framework of the Center for Technology, Innovation, and Community Engagement at Columbia University, and complements the ongoing efforts of the Chemistry Department and the University to reach the Harlem community.

该奖项根据 2009 年美国复苏和再投资法案（公法 111-5）提供资金。技术摘要本职业提案支持一项综合研究和教育计划，该计划的重点是使用理论和计算方法解决涉及胶体颗粒自组装的问题。 与该领域迄今为止所做的大多数工作重点关注给定局部粒子间相互作用如何产生秩序不同，这项研究将研究反问题，即找到构建块自组装成给定结构所需的局部相互作用。 使用这种方法，将开发新的策略来寻找能够通过自组装生成特定晶体结构的粒子相互作用。 还将研究弹性和两性表面在调节颗粒自组装中的作用以及颗粒聚集在确定软界面的机械和弹性性能中的作用。 以系统方式设计粒子相互作用以瞄准所需晶体的能力，以及操纵微观弹性片的机械性能的前景，将是具有重大实际意义的结果。这项研究的结果将有助于为具有新颖光学、机械和功能特性的结构的合理设计开辟道路。该职业奖的教育意义是多方面的。其中一个主要目标是通过改善附近哈林区高中的 K-12 课程活动来增加代表性不足的群体对科学尤其是化学领域的参与。 PI 还计划开发多平台互动教育软件，以视频游戏的特殊形式，向全国初中和高中免费提供。这种方法的前提是主动学习和互动将是激励和启发下一代科学家的关键。该外展计划建立在哥伦比亚大学技术、创新和社区参与中心的框架之上，补充了化学系和大学为接触哈莱姆社区所做的持续努力。非技术摘要该职业奖支持研究和教育相结合该计划开发理论和计算方法，可以预测分子构件如何自组装成三维材料结构。 这种方法可以应用于许多材料系统，一些代表性的例子包括：在大分子尺度上将蛋白质聚集成功能生物机器，形成病毒的蛋白质外壳，包装大分子以形成生物膜，以及组装纳米级颗粒以形成生物膜。制造光子晶体，这是为特定光学特性而设计的晶体，例如传输特定颜色的光并阻挡其他颜色的光。 主要研究目标包括开发数值工具来检查粒子如何相互作用才能自组装成所需的复杂晶体结构，研究弹性表面或膜如何协助粒子自组装，以及研究如何利用软界面上的粒子聚类来确定用作模板的材料的机械和弹性性能。 这项研究的结果有助于为具有新颖光学、机械和功能特性的结构的合理设计开辟道路。 该计划将建立在哥伦比亚大学对纳米技术领域的坚定承诺之上。该职业奖的教育意义是多方面的。其中一个主要目标是通过改善附近哈林区高中的 K-12 课程活动来增加代表性不足的群体对科学尤其是化学领域的参与。 PI 还计划开发多平台互动教育软件，以视频游戏的特殊形式，向全国初中和高中免费提供。这种方法的前提是主动学习和互动将是激励和启发下一代科学家的关键。该外展计划建立在哥伦比亚大学技术、创新和社区参与中心的框架之上，补充了化学系和大学为接触哈莱姆社区所做的持续努力。