MRI: Development of a 240 GHz Pulsed Electron Paramagnetic Resonance Spectrometer with Nanosecond Time Resolution

MRI：开发具有纳秒时间分辨率的 240 GHz 脉冲电子顺磁共振波谱仪

• 批准号: 0821589
• 负责人: Song-I Han
• 金额: $ 125.46万
• 依托单位: University of California-Santa Barbara
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0821589&HistoricalAwards=false
• 关键词: MRI; Development; 240; GHz; Pulsed

The Department of Chemistry and Biochemistry at the University of California-Santa Barbara will develop a 240 GHz pulsed electron paramagnetic resonance spectrometer (EPR) with this award from the Major Research Instrumentation (MRI) program. This high frequency EPR spectrometer will capitalize on the tunable terahertz excitation pulses generated at UC Santa Barbara's Free Electron Laser (FEL) facility. The instrument will push the frontier of EPR spectroscopy to more than twice the current frequency/field limitation. It will open up new areas of investigation of the structure and dynamics in biological, chemical and electronic systems. EPR spectroscopy detects changes in electron spin in materials that contain an unpaired electron. This provides information on the structure and motions of the material at an atomic level. The resultant data provides insight on the properties of materials such as proteins, enzymes and defects in solid materials. This new instrument will allow the study of proteins in biologically relevant environments that were heretofore impossible in many cases. After development, the new spectrometer is intended to become a multi-user facility because of its unique capabilities. Graduate and undergraduate students will be involved in this project learning skills in the design and construction of state-of-the-art instrumentation.

加州大学圣塔芭芭拉分校化学与生物化学系将获得重大研究仪器 (MRI) 计划的奖项，开发 240 GHz 脉冲电子顺磁共振波谱仪 (EPR)。 这种高频 EPR 光谱仪将利用加州大学圣巴巴拉分校的自由电子激光 (FEL) 设施产生的可调谐太赫兹激发脉冲。 该仪器将把 EPR 光谱学的前沿推向当前频率/场限制的两倍以上。 它将开辟生物、化学和电子系统结构和动力学研究的新领域。 EPR 光谱检测包含不成对电子的材料中电子自旋的变化。 这提供了有关原子水平上材料的结构和运动的信息。 由此产生的数据提供了对蛋白质、酶和固体材料缺陷等材料特性的深入了解。 这种新仪器将允许在生物学相关环境中研究蛋白质，而这在许多情况下是迄今为止不可能实现的。 开发完成后，新型光谱仪因其独特的功能而旨在成为多用户设施。 研究生和本科生将参与该项目，学习最先进仪器的设计和建造技能。