CAREER: Expanding the Science of Complex Fluids to the Solid State

职业：将复杂流体科学扩展到固态

• 批准号: 0744650
• 负责人: Carlos Co
• 金额: --
• 依托单位: University of Cincinnati Main Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0744650&HistoricalAwards=false
• 关键词: CAREER; Expanding; Science; Complex; Fluids

CBET- 0744650Carlos C. CoU. Cincinnati Complex fluid mixtures of surfactants with water and oil self-assemble to form a rich variety of nanostructures that have found important applications in many areas of chemical and materials engineering. Over the past three years, the PI's laboratory has pioneered investigations of a completely new class of anhydrous complex fluids, comprising of surfactant, oil, and sugar that form solid complex glasses. The robust nanostructure of these sugar-based complex glasses, and the ease with which they can be dissolved afterwards in water, make them eminently useful as templates for the preparation of rod-like, sheet-like, and bicontinuous nanomaterials with wide ranging practical applications. The thermodynamically driven spontaneous mixing of hydrophobic compounds in complex glasses also opens new avenues for direct encapsulation of oils and preservation of pharmaceuticals and proteins. Results from the proposed work to understand glass formation in sugar-based complex glasses will establish the foundation for a broader career-defining research program in glass formation from non-aqueous complex fluids including for example, molten salts and low melting point metal alloys that combine magnetic, electronic, and catalytic properties with the rich nanostructures of complex fluids. New science and exciting applications await discovery at the intersection of glasses with complex fluids. This CAREER proposal seeks support that will catalyze efforts towards establishing the fundamental principles underlying glass formation in complex fluids. An array of preliminary results demonstrates glass formation in complex fluids and the feasibility of the proposed studies. These include: (1) phase behavior characterization; (2) modulated differential scanning calorimetry measurements of the glass transition; (3) electron microscopy; (4) small angle scattering measurements of microstructural length scales; (5) magnetic resonance imaging and self-diffusion measurements of microstructural topology/connectivity; and (6) rheological characterization of the complex glasses in their molten state. To demonstrate the practical utility of these complex glasses, the PI presents preliminary results for two specific applications: (1) environmentally friendly, solvent-free preparation of polydivinylbenzene membranes, and (2) high-efficiency, spontaneous encapsulation of 50 vol% limonene, the principal component of orange oil, in an edible solid microemulsion glass. Broader Impact: The educational objective proposed here further integrates the PI's research expertise to lead a curriculum reform effort that elevates product design, rooted at the molecular-level, to the same level as the archetypal Chemical Engineering capstone course in plant design. To bring together concepts taught in a sequence of new pilot courses, the PI will develop a common case study on laundry detergents, which ties together knowledge of colloids and interfacial phenomena, polymers, inorganic chemistry, enzyme catalysis, encapsulation, powder processing, and broader ecological and intellectual property considerations. Other academic institutions will access lecture and laboratory modules through the WWW and the PI will make a technically simplified available to K12 students and teachers. The PI will assess the effectiveness of this curriculum reform effort, which will be implemented in stages on two parallel undergraduate sections, through a mandatory annual cooperative education cycle. Student, faculty, and industrial evaluations will be used to fine-tune the course content and test the commonly held belief that innovative product design has become a necessary skill for domestic chemical engineers as traditional engineering functions and production are transferred overseas.

CBET- 0744650Carlos C. CoU。辛辛那提 表面活性剂与水和油的复杂流体混合物自组装形成丰富多样的纳米结构，这些纳米结构在化学和材料工程的许多领域都有重要的应用。在过去的三年里，PI 的实验室率先研究了一类全新的无水复杂流体，该流体由表面活性剂、油和糖组成，形成固体复杂玻璃。这些糖基复合玻璃具有坚固的纳米结构，并且易于溶解在水中，使其非常适合作为制备棒状、片状和双连续纳米材料的模板，具有广泛的实际应用。疏水性化合物在复杂玻璃中的热力学驱动自发混合也为直接封装油以及保存药物和蛋白质开辟了新途径。拟议的了解糖基复杂玻璃中玻璃形成的工作的结果将为更广泛的职业定义研究计划奠定基础，该研究计划是由非水复杂流体（包括例如熔盐和低熔点金属合金）形成玻璃的。复杂流体丰富的纳米结构具有磁性、电子和催化特性。新的科学和令人兴奋的应用等待着玻璃与复杂流体的交叉发现。该职业提案寻求支持，以促进建立复杂流体中玻璃形成的基本原理。一系列初步结果证明了复杂流体中玻璃的形成以及所提出研究的可行性。其中包括：（1）相行为表征； (2) 玻璃化转变的调制差示扫描量热法测量； (3)电子显微镜； (4) 微观结构长度尺度的小角散射测量； (5) 微观结构拓扑/连通性的磁共振成像和自扩散测量； (6)复杂玻璃在熔融状态下的流变特性。为了证明这些复杂玻璃的实用性，PI 展示了两个具体应用的初步结果：(1) 环保、无溶剂的聚二乙烯基苯膜制备，以及 (2) 50 vol% 柠檬烯的高效自发封装，橙油的主要成分，存在于可食用固体微乳液玻璃中。 更广泛的影响：这里提出的教育目标进一步整合了 PI 的研究专业知识，以领导课程改革工作，将植根于分子水平的产品设计提升到与工厂设计中典型的化学工程顶点课程相同的水平。为了将一系列新试点课程中教授的概念结合起来，PI 将开发一个关于洗衣粉的常见案例研究，它将胶体和界面现象、聚合物、无机化学、酶催化、封装、粉末加工和更广泛的知识联系起来生态和知识产权考虑。其他学术机构将通过 WWW 访问讲座和实验室模块，PI 将为 K12 学生和教师提供技术上的简化版本。项目负责人将评估这项课程改革工作的有效性，该课程改革将通过强制性的年度合作教育周期分阶段在两个平行的本科生部分实施。学生、教师和行业评估将用于微调课程内容，并检验人们普遍认为，随着传统工程功能和生产向海外转移，创新产品设计已成为国内化学工程师的必备技能。