NIRT: Engineered Molecular Fluidics

NIRT：工程分子流体学

• 批准号: 0609087
• 负责人: Sergei Sheiko
• 金额: $ 116万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0609087&HistoricalAwards=false
• 关键词: NIRT; Engineered; Molecular; Fluidics

ABSTRACTProposal No.: 0609087Title: NIRT: Engineered Molecular FluidicsPI: Sheiko, Sergei S.Institution: University of North Carolina at Chapel HillThis proposal was received in response to Nanoscale Science and Engineering initiative, NSF 05-610, category NIRT. This project will explore a new direction in micro-fabricated fluidics molecular fluidics wherein one can monitor, probe, and manipulate flows one molecule at a time. Investigations will be performed on the behavior of fluid mono-layers residing on solid substrates that can be manipulated by both electric fields and intrinsic means such as the interaction with the substrate. The proposed approach is based on synthetic design of flow- and electric field-responsive molecules, experimental and theoretical studies of surface-confined macromolecules under flow, and the engineering of flow actuation techniques. The flow will be monitored over a broad range of length scales from the motion of the film front all the way down to the movements of individual molecules within the film. Since molecular conformation responds to flow and may respond to external stimuli such as electric fields, one anticipates the development of molecular devices that can both probe the flow properties and actively affect the flow structure. If successfully implemented, electrically controlled surfaces will lead to creation of a new range of materials and devices that enable anisotropic wetting, directional liquid transport, and anisotropic tribology, and may even be self-cleaning or direct the growth of live cells for biomaterials and implants. Experimental findings will be continuously tested against theoretical predictions and computer simulation studies, and will guide the synthesis of additional functional macromolecules. With respect to broader impacts, the proposed research will advance fundamental understanding of the conformation and dynamics of surface-confined polymer chains and lead to the development of new theories for interfacial flow and its interaction with electric fields. Furthermore, the highly interactive and efficient teamwork in the proposed multi-disciplinary research area will ensure maximum opportunity for integrating science and education based on the interdisciplinary training of student and postdocs, partnerships with 6-12 schools, and involvement of underrepresented groups. The collaborative education plan involves three areas of activity: (i) the development of a new graduate course and a new lab module, (ii) co-advising and an exchange of students that will experience a highly interdisciplinary education in polymer chemistry, advanced polymer theory, visualization and micro-fabrication techniques, (iii) and regular interactions with local high schools in form of introductory lectures and summer research programs at our universities. One of the most important goals is to bring molecular visualization from university to high-school classrooms where the ability to see molecules would be invaluable for the teaching of molecular structures and chemical reactions.

摘要提案编号：0609087标题：NIRT：工程分子流体PI：Sheiko，Sergei S.机构：北卡罗来纳大学教堂山分校此提案是为了响应纳米科学与工程倡议，NSF 05-610，NIRT 类别而收到的。 该项目将探索微制造流体学分子流体学的新方向，其中人们可以一次监测、探测和操纵一个分​​子的流动。将研究驻留在固体基质上的流体单层的行为，这些行为可以通过电场和固有手段（例如与基质的相互作用）来操纵。 所提出的方法基于流和电场响应分子的综合设计、流下表面约束大分子的实验和理论研究以及流驱动技术的工程。从薄膜前端的运动一直到薄膜内单个分子的运动，将在广泛的长度范围内监测流动。由于分子构象对流动做出响应，并且可能对电场等外部刺激作出反应，因此人们预计会开发出既可以探测流动特性又可以主动影响流动结构的分子装置。如果成功实施，电控表面将催生一系列新的材料和设备，这些材料和设备能够实现各向异性润湿、定向液体传输和各向异性摩擦学，甚至可能具有自清洁功能或指导生物材料和植入物活细胞的生长。实验结果将根据理论预测和计算机模拟研究不断进行测试，并将指导其他功能性大分子的合成。就更广泛的影响而言，拟议的研究将增进对表面限制聚合物链的构象和动力学的基本理解，并导致界面流动及其与电场相互作用的新理论的发展。此外，拟议的多学科研究领域的高度互动和高效的团队合作将确保在学生和博士后的跨学科培训、与 6-12 所学校的合作伙伴关系以及代表性不足群体的参与的基础上，最大限度地实现科学与教育的融合。合作教育计划涉及三个活动领域：(i) 开发新的研究生课程和新的实验室模块，(ii) 共同指导和交流学生，这些学生将体验高分子化学、先进聚合物等领域的高度跨学科教育理论、可视化和微加工技术，(iii) 并以介绍讲座和大学暑期研究项目的形式与当地高中定期互动。最重要的目标之一是将分子可视化从大学引入高中课堂，在高中课堂中观察分子的能力对于分子结构和化学反应的教学来说是非常宝贵的。