SGER: Development of Dynamic Diamond Anvil Cell Spectroscopy

SGER：动态金刚石砧细胞光谱学的发展

• 批准号: 0612957
• 负责人: Eric Chronister
• 金额: --
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0612957&HistoricalAwards=false
• 关键词: SGER; Development; Dynamic; Diamond; Anvil

The Experimental Physical Chemistry Program of the Chemistry Division funds this Small Grant for Exploratory Research (SGER). Professor Eric Chronister of the University of California, Riverside and his graduate students will address design issues relevant to optimizing the response time and maximum load of a dynamic diamond anvil cell (DAC). The goal of this work is to develop a cell with unique capabilities for initiating fast (microsecond timescales) and reversible high-pressure (~30 kbar) changes and rapid pressure cycling. The performance of the dynamic DAC will be characterized using the pressure dependence of the emission lines of ruby doped into a polymer. Spatially patterned polymer samples will allow determination of both the temporal and spatial characteristics of the pressure changes. Applications for the proposed dynamic DAC include dynamic pressure jump studies of polymers and glasses, pressure-jump studies of protein folding, and kinetic studies of pressure-induced polymorphic phase transitions. Pressure-jump studies of protein folding and unfolding on microsecond timescales under physiological conditions would provide a useful alternative to temperature-jump experiments. The ability to study pressure cycling at high repetition rates also would offer a unique approach to accelerating and studying aging processes in materials.

化学部的实验物理化学计划为探索性研究（SGER）提供了小额赠款。 加利福尼亚大学，里弗赛德大学及其研究生埃里克·克罗纳斯特（Eric Chronister）教授将解决与优化响应时间和最大负载有关的设计问题，并最大程度地负载了动态钻石小组（DAC）。 这项工作的目的是开发具有启动快速（微秒时标）和可逆的高压（〜30 kbar）变化和快速压力循环的独特功能的单元。 动态DAC的性能将使用掺杂到聚合物的红宝石的发射线的压力依赖性来表征。 空间图案化的聚合物样品将允许确定压力变化的时间和空间特征。 提出的动态DAC的应用包括聚合物和玻璃的动态压力跳跃研究，蛋白质折叠的压力跳跃研究以及压力诱导的多态性相变的动力学研究。蛋白质折叠和在生理条件下微秒时间尺度上展开的压力跳跃研究将为温度跳跃实验提供有用的替代方法。以高重复率研究压力循环的能力也将提供一种独特的方法来加速和研究材料中的衰老过程。