Filament Dynamics in Three-Dimensional Reaction-Diffusion Systems

三维反应扩散系统中的细丝动力学

• 批准号: 0513912
• 负责人: Oliver Steinbock
• 金额: $ 44.75万
• 依托单位: Florida State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0513912&HistoricalAwards=false
• 关键词: Filament; Dynamics; Three; Dimensional; Reaction

Oliver Steinbock of Florida State University is suuported by a grant from the Theoretical and Computational Chemistry program wihin the Division of Chemistry for research on filament dynamics in three dimensional reaction-diffusion systems. A systematic study of three dimensional chemical waves in a variant of the Belousov-Zhabotinsky (BZ) reaction is being carried out to test theoretical predictions of interesting scroll waves rotating around circular filaments and other complex wave dynamics. These new experiments are significantly expanding the number of experimental studies of this important reaction thought to be a model for excitable media in biological systems, such as cardiac and neural tissue. Steinbock's research group is devising new experiemental strategies that will allow the controlled fabrication of heterogeneous three dimensional systems that may mimic the heterogeneities found in biological tissue. Cardiac tissue, in particular, is suggested to have the same type of dynamical properties as the BZ medium, so broader impacts are expected in the understanding of sudden cardiac death, shown in prior theoretical studies to be related to the filament dynamics to be studied here.

佛罗里达州立大学的奥利弗·斯坦博克（Oliver Steinbock）获得了理论和计算化学计划的赠款。正在对Belousov-Zhabotinsky（BZ）反应的变体中的三维化学波进行系统研究，以测试围绕圆形细丝和其他复杂波动力学旋转的有趣滚动波的理论预测。这些新的实验显着扩大了这种重要反应的实验研究数量，认为这是生物系统中可激发培养基的模型，例如心脏和神经组织。 Steinbock的研究小组正在制定新的体验策略，这些策略将允许对可能模仿生物组织中发现的异质性的异质三维系统进行控制。尤其是心脏组织被认为具有与BZ培养基相同的动力学特性，因此预期在理解突然心脏死亡中会产生更广泛的影响，在先前的理论研究中表明，此处应研究与细丝动力学有关。