MRI/RUI(Chemistry): Development of High Speed Gas Chromatography - Multiplex Coherent Raman Spectroscopy

MRI/RUI（化学）：高速气相色谱的发展 - 多重相干拉曼光谱

• 批准号: 0116384
• 负责人: Peter Chen
• 金额: $ 31.68万
• 依托单位: Spelman College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116384&HistoricalAwards=false
• 关键词: MRI; RUI; Chemistry; Development; Speed

With support from the Major Research Instrumentation (MRI) Program, Prof. Peter C. of Spelman College will develop a state-of-the-art high speed (100 Hz) Raman-based spectroscopic detector to identify eluents from a high speed gas chromatograph (GC). The resulting instrument will be capable of rapid and accurate identification of GC eluents, able to distinguish among isomers and provide functional group information. Potential applications include a) analysis of air, water or sediment for pollutants; analysis of unknown reation products or compounds found in natural products; c) study of the degradation products of pesticides and herbicides; d) analysis of petroleum products, for example, the presence or fate of additives such as MTBE in groundwater; e) study of the presence or fate of additives or allergens in foods, flavors, feedstock and fragrances; and f) study of polymer decomposition and degassing upon heating. These studies will also provide intensive research training for undergraduate students who are members of underrepresented groups. Tandem techniques that interface chromatography with spectroscopic detectors are among the most powerful tools available for analyzing mixtues. By combining two techniques, tandem instruments can overcome the limitations of a single technique, for example spectral congestion due to mixtures, or difficulty identifying unknown species using only chromatographic retention times. This high speed GC/Raman instrument will advance the knowledge in high speed separation science, and find applications in many areas of science, including materials chemistry and environmental sciences.

在主要研究仪器 (MRI) 项目的支持下，斯佩尔曼学院的 Peter C. 教授将开发一种最先进的高速 (100 Hz) 拉曼光谱检测器，用于识别高速气相色谱仪中的洗脱液（GC）。 由此产生的仪器将能够快速、准确地识别 GC 洗脱液，能够区分异构体并提供官能团信息。 潜在应用包括 a) 分析空气、水或沉积物中的污染物；分析天然产物中发现的未知反应产物或化合物； c) 农药和除草剂降解产物的研究； d) 石油产品分析，例如地下水中 MTBE 等添加剂的存在或归宿； e) 研究食品、香料、原料和香料中添加剂或过敏原的存在或归宿； f) 加热时聚合物分解和脱气的研究。 这些研究还将为代表性不足群体的本科生提供强化研究培训。 将色谱法与光谱检测器连接的串联技术是可用于分析混合物的最强大的工具之一。 通过结合两种技术，串联仪器可以克服单一技术的局限性，例如由于混合物导致的光谱拥塞，或仅使用色谱保留时间难以识别未知物种。 这款高速 GC/拉曼仪器将推进高速分离科学的知识发展，并在许多科学领域得到应用，包括材料化学和环境科学。