Integrating NMR Spectroscopy into the Chemistry Curriculum

将核磁共振波谱学纳入化学课程

• 批准号: 9750847
• 负责人: Holly Gaede
• 金额: $ 10万
• 依托单位: Ursinus College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 1999-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9750847&HistoricalAwards=false
• 关键词: Integrating; NMR; Spectroscopy; into; Chemistry

The use of nuclear magnetic resonance (NMR) spectroscopy to study molecular structure and dynamics is now an essential element of an effective undergraduate chemistry education. Students without access to a modern NMR spectrometer cannot gain experience in multinuclear, Fourier transform, and multidimensional NMR. Moreover, even with access to a modern instrument, students all too often learn only about structural elucidation with NMR spectroscopy in Organic Chemistry and never about NMR as a tool for studying dynamics. In this project, NMR spectroscopy is implemented vertically throughout the curriculum. The new spectrometer is incorporated into nearly every chemistry laboratory beginning in the first year with Organic Chemistry, where students familiarize themselves with the instrument and learn basic spectral interpretation. As students progress to Analytical, Physical, and Advanced Inorganic courses, the sophistication of the experiments and the number of parameters the student controls are increased. By the time a student participates in senior research, he or she has the skills to design a two-dimensional experiment without assistance. The spectrometer is used to reinforce concepts taught in the classroom, including stereochemistry, fluxionality, Fourier transform, equilibria, thermodynamics, and kinetics. An important aim of the project is to provide students with a perspective of the broad utility of NMR spectroscopy. In addition, the research program benefits from the extended capabilities of the spectrometer, and more of it can result in publication. The curriculum is also affected as new courses are added and multinuclear and solid-state experiments are developed and disseminated. Finally, students are better prepared for graduate school and industry. *

使用核磁共振 (NMR) 波谱研究分子结构和动力学现在已成为有效的本科化学教育的基本要素。 无法使用现代核磁共振波谱仪的学生无法获得多核、傅里叶变换和多维核磁共振的经验。 此外，即使拥有现代仪器，学生也常常只了解有机化学中核磁共振波谱的结构解析，而从未了解核磁共振作为研究动力学的工具。 在这个项目中，核磁共振波谱学在整个课程中垂直实施。 从有机化学第一年开始，几乎所有化学实验室都采用了新型光谱仪，学生可以熟悉该仪器并学习基本的光谱解释。 随着学生学习分析、物理和高级无机课程，实验的复杂性和学生控制的参数数量都会增加。 当学生参与高级研究时，他或她已经具备在没有帮助的情况下设计二维实验的技能。 光谱仪用于强化课堂上教授的概念，包括立体化学、流动性、傅里叶变换、平衡、热力学和动力学。 该项目的一个重要目标是为学生提供核磁共振波谱广泛用途的视角。 此外，该研究项目受益于光谱仪的扩展功能，并且更多的研究项目可以发表。 随着新课程的增加以及多核和固态实验的开发和传播，课程也受到影响。 最后，学生为研究生院和工业界做好更好的准备。 *