Brain-skull interface: discovering the missing piece of head biomechanics

脑-颅骨界面：发现头部生物力学缺失的部分

• 批准号: DP230100949
• 负责人: Prof Adam Wittek
• 金额: $ 39.97万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230100949
• 关键词: Brain; skull; interface; discovering; missing

Overall objective of this project is to measure, mathematically describe and implement in software mechanical properties of brain-skull interface – a critical component of current large and sophisticated computational models of the brain and the last missing piece of brain biomechanics knowledge. This will allow increased reliability of comprehensive biomechanical models used to simulate realistic injury and surgery scenarios. The problem is significant and urgent. Every year in Australia, there are over 22,000 cases of traumatic brain injury, some of which could be prevented by better passive and active countermeasures; and over 12,000 neurosurgical procedures that surgical simulation could make more accurate and therefore safer.

该项目的总体目标是测量、数学描述并在软件中实现脑-颅骨界面的机械特性，这是当前大型复杂的大脑计算模型的关键组成部分，也是大脑生物力学知识的最后一个缺失部分。用于模拟真实损伤和手术场景的综合生物力学模型的可靠性。 这个问题在澳大利亚每年都会发生超过 22,000 例脑外伤病例，其中一些可以通过更好的被动和主动对策来预防；并且手术模拟可以使超过 12,000 例神经外科手术变得更加准确，因此更加安全。 。